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lodoxamide tromethamine (Alomide)
an orphan drug; structure
Also Known As:
Alomide
; U 42585 E; U-42,585E; 2,2'-((2-chloro-5-cyano-1,3-phenylene)diimino)bis(2-oxoacetic acid), compd. with 2-amino-2- (hydroxymethyl)-1,3-propanediol (1:2)
Networked:
18
relevant articles (
7
outcomes,
5
trials/studies)
Relationship Network
Drug Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Aldehydic Acids
Glyoxylates
Oxamic Acid: 12
lodoxamide tromethamine: 18
Alcohols: 595
Glycols: 38
Propylene Glycols: 2
Tromethamine: 382
lodoxamide tromethamine: 18
Nitriles: 227
lodoxamide tromethamine: 18
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Oxamic Acid: 12
lodoxamide tromethamine: 18
Experts
1.
Nicoară, S
: 1 article (01/2001)
2.
Lin, Z
: 1 article (09/2000)
3.
Zhang, W
: 1 article (09/2000)
Related Diseases
1.
Allergic Conjunctivitis (Giant Papillary Conjunctivitis)
09/01/2000 - "
Our study suggests that alomide is a safe and effective drug in the treatment of allergic conjunctivitis.
"
01/01/2001 - "
The ocular status of each patient has been evaluated with a score: the intensity of each symptom and sign has been graded between 1-3. In all cases, the use of Alomide induced the improvement of the typical symptoms and signs of the allergic conjunctivitis.
"
10/01/1998 - "
Lodoxamide tromethamine and N-acetyl-aspartyl glutamic acid (NAAGA) are mast cell stabilisers, both of which have been shown to be effective in the treatment of allergic conjunctivitis.
"
06/01/1999 - "
A double-masked, randomized, placebo-controlled study was conducted to evaluate the effectiveness of lodoxamide tromethamine 0.1% eyedrops in preventing inflammatory cell accumulation in the tear fluid of patients with vernal conjunctivitis.
"
01/01/2001 - "
Evaluating the efficiency and safety of Alomide (lodoxamide 01.%) in the treatment of allergic conjunctivitis.
"
2.
Keratoconjunctivitis
09/01/1995 - "
Topically applied lodoxamide tromethamine 0.1% is useful in the treatment of superior limbic keratoconjunctivitis.
"
09/01/1995 - "
We studied the efficacy of topically applied lodoxamide tromethamine 0.1% in the treatment of superior limbic keratoconjunctivitis.
"
09/01/1995 - "
Lodoxamide tromethamine treatment for superior limbic keratoconjunctivitis.
"
07/01/1998 - "
Clinical studies carried out in 170 patients demonstrated a high efficacy of alomide in the treatment of subacute and chronic pollenosis conjunctivitis, spring keratoconjunctivitis, multiple and toxic allergic keratitis, and other allergic conjunctivities.
"
07/01/1998 - "
[Alomide eyedrops in the treatment of allergic conjunctivitis and keratoconjunctivitis].
"
3.
Asthma (Bronchial Asthma)
07/01/1985 - "
The efficacy of lodoxamide tromethamine in the treatment of asthma was studied in a 16-week double-blind, placebo-controlled study of 68 perennial allergic subjects with asthma.
"
07/01/1985 - "
Inhaled lodoxamide tromethamine in the treatment of perennial asthma: a double-blind placebo-controlled study.
"
07/01/1985 - "
Thus, although lodoxamide tromethamine possesses potent mast cell-stabilizing activity in vitro, we have failed to demonstrate any useful long-term effect in the treatment of mild allergic asthma.
"
06/01/1986 - "
A most active biologue of disodium cromoglycate (DSCG) available, lodoxamide tromethamine (LT), has been studied and characterized pharmacologically, in animal and human models of asthma.
"
12/01/1981 - "
Lodoxamide tromethamine, a new cromolyn-like drug, was studied to determine its effectiveness and duration of action in preventing antigen-induced bronchospasm in 15 subjects with clinically stable extrinsic asthma.
"
4.
Keratitis
07/01/1998 - "
Clinical studies carried out in 170 patients demonstrated a high efficacy of alomide in the treatment of subacute and chronic pollenosis conjunctivitis, spring keratoconjunctivitis, multiple and toxic allergic keratitis, and other allergic conjunctivities.
"
5.
Conjunctivitis
07/01/1998 - "
Clinical studies carried out in 170 patients demonstrated a high efficacy of alomide in the treatment of subacute and chronic pollenosis conjunctivitis, spring keratoconjunctivitis, multiple and toxic allergic keratitis, and other allergic conjunctivities.
"
Related Drugs and Biologics
1.
Cromolyn Sodium (Cromoglicic Acid)
2.
Reactive Oxygen Species (Oxygen Radicals)
3.
Xanthine Oxidase
4.
Solutions
5.
Allopurinol (Remid)
6.
isospaglumic acid (NAAGA)
7.
Ophthalmic Solutions (Eye Drops)
8.
lodoxamide ethyl (lodoxamide)
9.
Mast Cell Stabilizers
10.
Antigens
Related Therapies and Procedures
1.
Injections
2.
Contact Lenses