|1.||Kumar, R: 1 article (06/2011)|
|2.||Dhanda, V: 1 article (06/2011)|
|3.||Vohra, H: 1 article (06/2011)|
|4.||Nizet, Victor: 1 article (03/2008)|
|5.||Chhatwal, G S: 1 article (03/2008)|
|6.||Wilson, Mark R: 1 article (03/2008)|
|7.||Walker, Mark J: 1 article (03/2008)|
|8.||Gillen, Christine M: 1 article (03/2008)|
|9.||Rohde, Manfred: 1 article (03/2008)|
|10.||Guzman, Carlos A: 1 article (03/2008)|
|1.||Pharyngitis (Sore Throat)
06/01/2011 - "Fifty GAS isolated consecutively, from children with mild pharyngitis (20), severe pharyngitis (24) and asymptomatic pharyngeal carriers (6), were characterized by emm typing and opacity factor (OF). "
10/01/1989 - "In August 1988, following a luncheon, an explosive epidemic of pharyngitis due to group A streptococci (M type 11, T type 3/13/B3264 and opacity factor positive) occurred among the staff of an institution in Ankara. "
03/01/1985 - "Production of serum-opacity factor by Streptococcus pyogenes strains isolated from pharyngitis in children. "
03/01/1973 - "This antibody was detected among patients convalescent from streptococcal sore throat in two communities in which outbreaks due to opacity factor-producing strains of group A streptococci occurred.In"
04/01/1999 - "Serum opacity factor (SOF) is a fibronectin-binding protein of group A streptococci that opacifies mammalian sera and is expressed by some strains that cause impetigo, pharyngitis and acute glomerulonephritis. "
03/07/2008 - "Serum opacity factor (SOF) is a unique multifunctional virulence determinant expressed at the surface of Streptococcus pyogenes and has been shown to elicit protective immunity against GAS infection in a murine challenge model. "
01/01/1990 - "Serotyping of strains collected consecutively from localized infections revealed a marked predominance of T-type 1, opacity factor negative strains (T-1 OF-), ranging from 41% in North Norway to 87% in Mid-Norway. "
04/01/2001 - "The presence of the anti-opacity factor (anti-OF) antibody (Ab) in the serum used for identifying the OF antigen (Ag) type represents previous or current infection with group A streptococci (GAS) of the OF Ag type. "
04/01/1990 - "In addition, the expression of the class II M protein molecule (one of two broad antigenic classes of the major virulence factor) and opacity factor (a lipoproteinase) was almost invariably accompanied by human IgG binding, regardless of tissue site of infection. "
|3.||Wounds and Injuries (Trauma)
05/01/1993 - "However, the cook who prepared the macaroni and cheese had a hand wound; a wound culture grew GAS with the same T agglutination pattern and M- and/or opacity factor type as that of all available GAS strains from ill attendees. "
01/15/2003 - "pyogenes type M-75, T-25, which was opacity factor positive, was isolated from throat swab specimens obtained from 5 of 57 inmates with primary cases and from 4 of 15 inmates with secondary cases, as well as from specimens obtained from the hand wounds and throat of one of the food handlers. "
|4.||Rheumatic Fever (Acute Articular Rheumatism)
11/01/1994 - "The composition of distinct emm sequence clusters generally parallels the ability of strains to express serum opacity factor and in some cases historical associations of certain M types with acute rheumatic fever, but not with M types classified as nephritogenic. "
03/01/1985 - "Strains were first tested for the production of streptococcal serum-opacity factor and, among those scored as OF-negative, the presence was then verified of M types which have been epidemiologically related to rheumatic fever. "
08/01/1977 - "Many of these strains were "pyoderma" serotypes, whereas others exhibited a characteristic (production of opacity factor) recently reported to be associated with decreased immunogenicity. "
10/01/1988 - "A series of 698 strains of group A beta-haemolytic streptococci (GAS) isolated from children with streptococcal pyoderma was tested for production of serum opacity factor (OF) and nicotinamide adenine dinucleotide glycohydrolase (NADase). "
|1.||NAD+ Nucleosidase (NAD(P) Nucleosidase)
|3.||Immunoglobulin G (IgG)
|5.||Carrier Proteins (Binding Protein)