|1.||Mori, Ikue: 3 articles (06/2012 - 12/2006)|
|2.||Ohnishi, Tetsuo: 3 articles (10/2011 - 05/2007)|
|3.||Yoshikawa, Takeo: 3 articles (10/2011 - 05/2007)|
|4.||Bersudsky, Yuly: 2 articles (04/2015 - 04/2006)|
|5.||Agam, Galila: 2 articles (04/2015 - 02/2005)|
|6.||Das, Amit Kumar: 2 articles (12/2014 - 04/2011)|
|7.||Dutta, Debajyoti: 2 articles (12/2014 - 04/2011)|
|8.||Bhattacharyya, Sudipta: 2 articles (12/2014 - 04/2011)|
|9.||Kuhara, Atsushi: 2 articles (06/2012 - 12/2006)|
|10.||Tanizawa, Yoshinori: 2 articles (06/2012 - 12/2006)|
|1.||Bipolar Disorder (Mania)
06/01/1995 - "Inositol monophosphatase inhibitors: a novel treatment for bipolar disorder?"
10/01/2011 - "The human IMPA2 gene encoding myo-inositol monophosphatase 2 is highly implicated with bipolar disorder but the substrates and the reaction mechanism of myo-inositol monophosphatase 2 have not been well elucidated.9 In the present study, we constructed 3D models of three- and two-Mg(2+)-ion bound myo-inositol monophosphatase 2, and studied substrate-binding manners using the docking program AutoDock3. "
01/01/2010 - "Among its targets is the inositol monophosphatase gene IMPA2, which has also been associated with risk of bipolar disorder in some family studies, and our observations offer a cellular signalling pathway in which PO activity and IMPA2 gene expression converge."
12/01/2014 - "As such, characterizing the regulation of the gene encoding inositol monophosphatase at the molecular level can help to understand the bipolar disorder. "
12/01/2010 - "Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder."
|2.||Mood Disorders (Mood Disorder)
03/01/2001 - "In our search for candidate genes for affective disorder on the short arm of chromosome 18, we cloned IMPA2, a previously unreported myo-inositol monophosphatase gene, that maps to 18p11.2. We determined its genomic structure and detected three new single nucleotide polymorphisms (SNPs). "
01/01/2005 - "Association study of myo-inositol monophosphatase 2 (IMPA2) polymorphisms with bipolar affective disorder and response to lithium treatment."
08/01/1997 - "Inositol and its synthetic enzyme, inositol monophosphatase, were measured in postmortem brain samples of 10 suicide victims, eight patients with bipolar affective disorder, and 10 normal comparison subjects. "
07/01/1991 - "K-76COONa may be useful for further investigation of the mechanism of myo-inositol monophosphatase and for determination of whether inhibition of this enzyme plays a role in the therapeutic effectiveness of lithium in treatment of affective disorders."
11/01/2001 - "Reduced inositol monophosphatase (IMPase) activity and elevated basal intracellular calcium levels ([Ca(2+)](B)) have been reported in B lymphoblast cell lines (BLCLs) from bipolar I affective disorder (BD-I) patients, which may reflect cellular endophenotypes of this disorder. "
07/01/2008 - "The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo."
07/01/2006 - "Herein we report that the SH2 domain-containing inositol phosphatase (SHIP) is phosphorylated upon infection of primary murine macrophages with the genetically related F. "
05/01/2014 - "In the present study, we confirmed targeting of the Src homology 2-containing inositol phosphatase 1 (SHIP1) 3' untranslated region (UTR) by miR-155 in the context of JEV infection. "
09/01/2015 - "The host gene, FgHal2, which has a highly conserved 3'-phosphoadenosine 5'-phosphatase (PAP phosphatase-like) domain or inositol monophosphatase (IMPase) superfamily domain, shows reduced expression in response to FgV1 infection. "
|4.||Alzheimer Disease (Alzheimer's Disease)
|5.||Schizophrenia (Dementia Praecox)
03/01/2001 - "Evidence for association of the myo-inositol monophosphatase 2 (IMPA2) gene with schizophrenia in Japanese samples."
09/15/1998 - "Cerebrospinal fluid inositol monophosphatase: elevated activity in depression and neuroleptic-treated schizophrenia."
01/01/1997 - "Increased erythrocyte inositol monophosphatase activity in schizophrenia."
05/15/2007 - "Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures."
|2.||5'-Nucleotidase (5' Nucleotidase)
|5.||3' Untranslated Regions (3' UTR)
|8.||Proteins (Proteins, Gene)
|9.||Inosine Monophosphate (IMP)
|10.||Shc Signaling Adaptor Proteins
|1.||Drug Therapy (Chemotherapy)