|1.||Su, Chin-Cheng: 12 articles (12/2014 - 09/2008)|
|2.||Xu, Min: 11 articles (02/2015 - 04/2009)|
|3.||Liu, Peiqing: 8 articles (07/2014 - 11/2011)|
|4.||Zhang, Bo: 8 articles (01/2013 - 04/2009)|
|5.||Zhang, Yong: 8 articles (04/2011 - 04/2009)|
|6.||Zhang, Li: 7 articles (01/2014 - 11/2009)|
|7.||Li, Jian: 6 articles (01/2016 - 11/2010)|
|8.||Wang, Yan: 6 articles (06/2015 - 12/2008)|
|9.||Kim, Sung-Hoon: 6 articles (07/2014 - 01/2010)|
|10.||Xu, Suowen: 6 articles (07/2014 - 11/2011)|
|1.||Brain Ischemia (Cerebral Ischemia)
05/01/2009 - "The objective of this study was to evaluate whether Tanshinone IIA (TSA) was neuroprotective in permanent focal cerebral ischemia and to determine the possible mechanisms of its neuroprotection. "
11/20/2013 - "Interestingly, tanshinone IIA is used as a prescription drug in China to address cerebral ischemia in patients. "
09/01/2013 - "The effect of cationic albumin-conjugated PEGylated tanshinone IIA nanoparticles on neuronal signal pathways and neuroprotection in cerebral ischemia."
01/01/2013 - "Tanshinone IIA is a good candidate for treating cerebral ischemia, but its short half-life and poor permeability across the blood-brain-barrier (BBB) limit its curative efficacy. "
07/01/2010 - "To investigate the underlying neuroprotective mechanisms of Tanshinone II A (TSA) on rat cerebral ischemia in vivo. "
04/01/2015 - "Tanshinone IIA is a lipophilic abietane diterpene compound, which exhibits protective effects against ischaemia/reperfusion injury; however, the pathways responsible for the myocardial protective activities of tanshinone IIA remain to be elucidated. "
12/01/2010 - "Tanshinone IIA may be a novel therapeutic agent for cerebral ischemia-reperfusion injury."
12/25/2012 - "The present study established a rat model of spinal cord ischemia/reperfusion injury and intraperitoneally injected Tanshinone IIa, 0.5 hour prior to model establishment. "
01/15/2015 - "Recent reports have shown that Tanshinone IIA has neuroprotective effects against cerebral ischemia/reperfusion injury and traumatic injury of the spinal cord in rats. "
07/01/2014 - "Anti-inflammatory effect of tanshinone I in neuroprotection against cerebral ischemia-reperfusion injury in the gerbil hippocampus."
06/01/2001 - "It was found that 3. 125-200 microliters.ml-1 tanshinone possessed obvious protective effects on PC12 cells from six ischemia-like injury models. "
06/01/2001 - "To investigate the protective effects of tanshinone on ischemia-like injury models. "
01/01/2010 - "Our results showed that tanshinone IIA relieved ischemia-induced injury by improving the cardiac function. "
04/01/2015 - "In conclusion, the results of the present study indicated that JAK2/STAT3 inhibitors may enhance the protective effect of tanshinone IIA on cardiac myocytes from hypoxic ischemia-induced injury, therefore suggesting that JAK2/STAT3 inhibitors may have a potential application in combination therapies with tanshinone IIA."
04/01/2015 - "Furthermore, tanshinone IIA and JAK2/STAT3 inhibitors in combination augmented the protection of myocardial cells from apoptosis induced by ischemia/reperfusion preconditioning in vivo. "
|4.||Myocardial Ischemia (Ischemic Heart Diseases)
01/01/2015 - "Although there were reports on the protective functions of tanshinone IIA (TSA) on rat myocardial ischemia, the exerting mechanism has not been completely clarified. "
05/01/2009 - "Cardioprotective effects of tanshinone IIA on myocardial ischemia injury in rats."
04/01/2011 - "Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways."
01/01/2015 - "Protective effects of tanshinone IIA on myocardial ischemia reperfusion injury by reducing oxidative stress, HMGB1 expression, and inflammatory reaction."
03/08/2011 - "Tanshinone IIA (T), salvianolic acid B (S) and ginsenoside Rb1 (G) are the three major active ingredients of Compound Danshen Formula (CDF) for its protective effects on myocardial ischemia (MI). "
|5.||Cardiovascular Diseases (Cardiovascular Disease)
05/01/2015 - "Tanshinone IIA (TSN) is one of the main components isolated from Danshen, which is widely used for the treatment of cardiovascular diseases. "
01/01/2014 - "Tanshinone IIA has definite protective effects on various cardiovascular diseases. "
01/01/2015 - "In this study, tanshinone extract powders from Salvia miltiorrhiza which are widely used for the treatment of cardiovascular diseases in the clinic are taken as the research object. "
11/01/2010 - "Our studies indicated that Tanshinone IIA (TanIIA), which is widely applied in the treatment of cardiovascular diseases with a rare occurrence of side effects, could promote APL cell differentiation and apoptosis. "
01/01/2016 - "Tanshinone IIA (TanIIA) is a traditional Chinese agent and has been widely used for treatment of cardiovascular diseases. "
|1.||HMGB1 Protein (HMG1)
|3.||salvianolic acid B
|4.||Tretinoin (Retinoic Acid)
|7.||Glycogen Synthase Kinases
|9.||salicylhydroxamic acid (SHAM)
|10.||NF-kappa B (NF-kB)
|2.||Chinese Traditional Medicine (Traditional Chinese Medicine)
|5.||Surgical Instruments (Clip)