F-chemotactic peptide

potent chemoattractant for human neutrophils

Also Known As:

CHO-Nle-Leu-Phe-Nle-Tyr-Lys; F-peptide; FNLPNTL; FNleLFNleYK; N-formyl hexapeptide; N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys; fNle-Leu-Phe-Nle-Tyr-Lys; fNorleu-Leu-Phe-Norleu-Tyr-Lys; formylnorleucyl-leucyl-phenylalanyl-norleucyl-tyrosyl-lysine; L-Lysine, N(2)-(N-(N-(N-(N-(N-formyl-L-norleucyl)-L-leucyl)-L-phenylalanyl)-L-norleucyl)-L-tyrosyl)-

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - F-chemotactic peptide: 9

Experts

1.	Elvevold, Kjetil: 1 article (01/2016)
2.	Smedsrød, Bård: 1 article (01/2016)
3.	Snapkov, Igor: 1 article (01/2016)
4.	Sveinbjørnsson, Baldur: 1 article (01/2016)
5.	Øie, Cristina Ionica: 1 article (01/2016)
6.	Bergmann, Ralf: 1 article (09/2014)
7.	Mamat, Constantin: 1 article (09/2014)
8.	Mosch, Birgit: 1 article (09/2014)
9.	Pietzsch, Jens: 1 article (09/2014)
10.	Pretze, Marc: 1 article (09/2014)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 09/01/2014 - "Preliminary radiopharmacological studies regarding the metabolic stability of the peptides in cell culture supernatants and rat plasma were accomplished as well as the cellular association of the (18) F-peptide in erythropoietin-producing hepatoma cell line-A2-overexpressing human melanoma cells in vitro. "
2.	Hepatocellular Carcinoma (Hepatoma) 09/01/2014 - "Preliminary radiopharmacological studies regarding the metabolic stability of the peptides in cell culture supernatants and rat plasma were accomplished as well as the cellular association of the (18) F-peptide in erythropoietin-producing hepatoma cell line-A2-overexpressing human melanoma cells in vitro. "
3.	Neoplasms (Cancer) 01/01/1991 - "When human granulocytes were stimulated with the chemotactic peptide FNLPNTL (N-formyl-norleucyl-leucyl-phenylalanyl-norleucyl-tyrosinyl- lysin; in the presence of cytochalasin B), proteolytic enzymes were released which prevented activation of tumor-cell derived pro-uPA by plasmin. " 09/11/1989 - "Proteolytic enzymes released from granulocytes upon stimulation with the chemotactic N-formyl peptide FNLPNTL (in the presence of cytochalasin B) prevented activation of tumor cell single-chain urokinase-type plasminogen activator (pro-uPA) by plasmin. "
4.	Infections 09/30/2000 - "In addition, such humanized mice generated human CD8 coreceptor-dependent HLA-B27-restricted CTL with the same specificity for recognition of MV fusion (F) peptide RRYPDAVYL as reported for humans during natural MV infection. " 10/01/2007 - "We previously reported that a human parainfluenza virus 3 (HPIV3) F peptide effectively inhibits infection mediated by the HeV glycoproteins in pseudotyped-HeV entry assays more effectively than the comparable HeV-derived peptide, and we now show that this peptide inhibits live-HeV and -NiV infection. "
5.	Henipavirus Infections 10/01/2007 - "We previously reported that a human parainfluenza virus 3 (HPIV3) F peptide effectively inhibits infection mediated by the HeV glycoproteins in pseudotyped-HeV entry assays more effectively than the comparable HeV-derived peptide, and we now show that this peptide inhibits live-HeV and -NiV infection. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Erythropoietin
3.	Peptide Hydrolases (Proteases)
4.	Fibrinolysin
5.	Cytochalasin B
6.	Fluorescein (Funduscein)
7.	Fluorescein-5-isothiocyanate (FITC)
8.	Interleukin-6 (Interleukin 6)
9.	Urokinase-Type Plasminogen Activator (Urokinase)
10.	Proteins (Proteins, Gene)