|1.||Gross, W L: 6 articles (02/2005 - 01/2000)|
|2.||Schultz, H: 5 articles (02/2005 - 01/2000)|
|3.||Csernok, E: 5 articles (02/2005 - 01/2000)|
|4.||Schultz, Hendrik: 4 articles (09/2007 - 11/2004)|
|5.||Levy, Ofer: 3 articles (10/2014 - 10/2007)|
|6.||Domingues, Marco M: 3 articles (04/2014 - 02/2009)|
|7.||Castanho, Miguel A R B: 3 articles (04/2014 - 02/2009)|
|8.||Santos, Nuno C: 3 articles (04/2014 - 02/2009)|
|9.||Hubacek, Jaroslav A: 3 articles (01/2014 - 11/2002)|
|10.||Weiss, Jerrold P: 3 articles (11/2011 - 08/2007)|
01/01/1995 - "Protective effects of a recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in an animal model of gram-negative sepsis."
12/01/1994 - "Protective effects of an N-terminal fragment of bactericidal/permeability-increasing protein in rodent models of gram-negative sepsis: role of bactericidal properties."
02/01/2009 - "Now in phase III clinical trials, rBPI(21), a recombinant N-terminal fragment of the bactericidal/permeability-increasing protein (BPI), is a promising drug to reduce lesions caused by meningococcal sepsis. "
09/16/2000 - "Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. "
02/01/2008 - "Recombinant bactericidal/permeability-increasing protein inhibits endotoxin-induced high-mobility group box 1 protein gene expression in sepsis."
|2.||Otitis Media with Effusion
05/01/2000 - "In this study, the efficacy of bactericidal/permeability-increasing protein (BPI) was assessed in a rat model of chronic otitis media with effusion. "
05/01/2000 - "Bactericidal/permeability-increasing protein prevents mucosal damage in an experimental rat model of chronic otitis media with effusion."
04/01/2001 - "Efficacy of bactericidal/permeability-increasing protein in experimental otitis media with effusion in rats: a new therapy for mucosal infections."
|3.||Septic Shock (Toxic Shock Syndrome)
11/01/1994 - "Protective effects of a recombinant N-terminal fragment of bactericidal/permeability increasing protein on endotoxic shock in conscious rabbits."
04/01/1995 - "Protection against endotoxic shock by bactericidal/permeability-increasing protein in rats."
03/01/1994 - "The role of bactericidal/permeability-increasing protein in the treatment of primate bacteremia and septic shock."
11/01/1993 - "Molecular entities and strategies under development to combat septic shock include monoclonal antibodies to endotoxin, active immunization with lipid-A analogues, bactericidal permeability-increasing protein, interleukin inhibitors, and inhibitors of tumor necrosis factor-alpha. "
01/01/2014 - "We evaluated the role of single nucleotide polymorphisms for five genes: bactericidal permeability increasing protein (BPI; rs5743507), lipopolysaccharide-binding protein (LBP; rs2232618), toll-like receptor 4 (TLR4; rs4986790), heat shock protein 70 (HSP 70; rs2227956), and interleukin 6 (IL-6; rs1800795) in 598 children aged 0 to 19 years that were admitted to a paediatric intensive care unit with fever, systemic inflammatory response syndrome, sepsis, severe sepsis, septic shock, or multiple organ dysfunction syndrome. "
|4.||Acute Lung Injury
04/01/2005 - "To investigate the protective effects of bactericidal/permeability increasing protein simulated peptide (bactericidal neutralizing endotoxin protein, BNEP) on murine acute lung injury (ALI) induced by lipopolysaccharide (LPS). "
04/01/2005 - "[Protective effects of bactericidal/permeability increasing protein simulated peptide on murine acute lung injury induced by lipopolysaccharide]."
05/01/1994 - "Bactericidal/permeability-increasing protein ameliorates acute lung injury in porcine endotoxemia."
08/01/2001 - "To investigate the role of recombinant bactericidal/permeability-increasing protein (rBPI21) in the attenuation of the sepsis syndrome and acute lung injury associated with lower limb ischemia-reperfusion (I/R) injury. "
08/01/2001 - "Bactericidal/permeability-increasing protein attenuates systemic inflammation and acute lung injury in porcine lower limb ischemia-reperfusion injury."
08/01/1997 - "In this study, we determined if bactericidal/permeability-increasing protein (BPI) has any effects on the induction of these factors after hemorrhagic shock. "
04/01/1999 - "Recombinant human bactericidal/permeability-increasing protein (rBPI21) has antibacterial and antiendotoxin properties, reduces cytokine levels, and increases survival in animal models of hemorrhagic shock. "
08/01/1997 - "Bactericidal/permeability-increasing protein ameliorates hypercoagulability after hemorrhagic shock."
04/01/1995 - "This study was conducted to determine the role of gut-derived bacteria/endotoxin in the pathogenesis of the multiple-organ damage and mortality, the possible beneficial effect of recombinant bactericidal/permeability-increasing protein (rBPl21), and whether neutralizing endotoxemia by rBPl21 treatment influences tumor necrosis factor (TNF) formation in rats after hemorrhagic shock and resuscitation. "
07/01/1997 - "To determine the possible mechanisms underlying beneficial effect of recombinant bactericidal/permeability-increasing protein (rBPI) on acute lung injury response to blood loss, we used reverse transcription polymerase chain reaction to measure pulmonary tumor necrosis factor (TNF), interleukin 6 (IL-6) mRNA expression in a rat model of prolonged hemorrhagic shock (4.00 kPa, 180 min) followed by adequate resuscitation. "
|2.||Antineutrophil Cytoplasmic Antibodies (ANCA)
|3.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|5.||Proteins (Proteins, Gene)
|5.||Cardiopulmonary Bypass (Heart-Lung Bypass)