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Methylmalonyl-CoA carboxytransferase

Also Known As:

methylmalonyl-CoA carboxyltransferase; methylmalonyl-coenzyme A carboxyltransferase; transcarboxylase

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - One-Carbon Group Transferases
      - Carboxyl and Carbamoyl Transferases: 52
        Methylmalonyl-CoA carboxytransferase: 3

Experts

1.	Basseres, Tiago: 1 article (03/2017)
2.	Dos Santos, Elizabeth S: 1 article (03/2017)
3.	Machado, Marcel A: 1 article (03/2017)
4.	Makdissi, Fabio F: 1 article (03/2017)
5.	Surjan, Rodrigo C: 1 article (03/2017)
6.	Aigner, Achim: 1 article (01/2017)
7.	Appelhans, Dietmar: 1 article (01/2017)
8.	Ennen, Franka: 1 article (01/2017)
9.	Janke, Andreas: 1 article (01/2017)
10.	Michen, Susanne: 1 article (01/2017)

Related Diseases

1.	Inborn Urea Cycle Disorders 03/08/2017 - "An ornithine metabolism imbalance resulting from overexpression of Aurora Kinase A as a result of a single, recurrent heterozygous deletion on chromosome 19, common to all fibrolamellar carcinomas, can lead to a c-Myc and ornithine decarboxylase overexpression that results in ornithine transcarboxylase dysfunction with urea cycle disorder and subsequent hyperammonemia. "
2.	Hyperammonemia 03/08/2017 - "An ornithine metabolism imbalance resulting from overexpression of Aurora Kinase A as a result of a single, recurrent heterozygous deletion on chromosome 19, common to all fibrolamellar carcinomas, can lead to a c-Myc and ornithine decarboxylase overexpression that results in ornithine transcarboxylase dysfunction with urea cycle disorder and subsequent hyperammonemia. "
3.	Neoplasms (Cancer) 01/01/2017 - "To achieve targeted delivery into tumor cells expressing the epidermal growth factor receptor variant III (EGFRvIII), monobiotinylated anti-EGFRvIII scFv fused to a Propionibacterium shermanii transcarboxylase-derived biotinylation acceptor (P-BAP) is bioconjugated to mal-PPI through a novel coupling strategy solely based on biotin-neutravidin bridging. "
4.	Inflammation (Inflammations) 08/22/2023 - "The abnormally expressed arginase2 and ornithine transcarboxylase were further discovered in combination with time-course metabolic profiling in the SAP animal models, the decreased ornithine catabolites were found at a late stage of inflammation, but ornithine-associated metabolic enzymes were activated during the inflammatory process. "
5.	Carcinoma (Carcinomatosis) 03/08/2017 - "An ornithine metabolism imbalance resulting from overexpression of Aurora Kinase A as a result of a single, recurrent heterozygous deletion on chromosome 19, common to all fibrolamellar carcinomas, can lead to a c-Myc and ornithine decarboxylase overexpression that results in ornithine transcarboxylase dysfunction with urea cycle disorder and subsequent hyperammonemia. "

Related Drugs and Biologics

1.	Ornithine
2.	ErbB Receptors (EGF Receptor)
3.	Aurora Kinase A
4.	Ornithine Decarboxylase (Decarboxylase, Ornithine)
5.	Enzymes
6.	Biotin (Vitamin H)
7.	epidermal growth factor receptor VIII
8.	neutravidin