HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

maleylacetoacetate isomerase

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Isomerases: 463
    - cis-trans-Isomerases: 44
      - maleylacetoacetate isomerase: 4

Experts

1.	Gu, Yuan: 1 article (02/2012)
2.	Hines, Ronald N: 1 article (02/2012)
3.	James, Margaret O: 1 article (02/2012)
4.	Langaee, Taimour: 1 article (02/2012)
5.	Li, Wenjun: 1 article (02/2012)
6.	Simpson, Pippa: 1 article (02/2012)
7.	Stacpoole, Peter W: 1 article (02/2012)
8.	Eapen, C E: 1 article (10/2004)
9.	Jana, A K: 1 article (10/2004)
10.	Karnik, Deepali: 1 article (10/2004)

Related Diseases

1.	Tyrosinemias (Tyrosinemia) 06/15/1999 - "We have searched for mutations in the maleylacetoacetate isomerase gene in four cases of unexplained severe liver failure in infancy with clinical similarities to hereditary tyrosinemia type I (pseudotyrosinemia). " 10/01/2004 - "Classical tyrosinemia type I arises from a deficiency of fumarylacetoacetate hydrolase while the variant tyrosinemia type Ib results from a deficiency of maleylacetoacetate isomerase." 11/01/2023 - "Maleic acid is a biomarker for maleylacetoacetate isomerase deficiency; implications for newborn screening of tyrosinemia type 1."
2.	Liver Failure 06/15/1999 - "We have searched for mutations in the maleylacetoacetate isomerase gene in four cases of unexplained severe liver failure in infancy with clinical similarities to hereditary tyrosinemia type I (pseudotyrosinemia). "
3.	Neoplasms (Cancer) 02/01/2012 - "Glutathione transferase ζ 1 (GSTZ1), also known as maleylacetoacetate isomerase, catalyzes the penultimate step of tyrosine catabolism and metabolizes several α-halocarboxylic acids, including dichloroacetic acid (DCA), an investigational drug used for lactic acidosis and, recently, solid tumors. "
4.	Lactic Acidosis 02/01/2012 - "Glutathione transferase ζ 1 (GSTZ1), also known as maleylacetoacetate isomerase, catalyzes the penultimate step of tyrosine catabolism and metabolizes several α-halocarboxylic acids, including dichloroacetic acid (DCA), an investigational drug used for lactic acidosis and, recently, solid tumors. "

Related Drugs and Biologics

1.	Investigational Drugs
2.	Biomarkers (Surrogate Marker)
3.	Tyrosine (L-Tyrosine)
4.	Glutathione Transferase (Glutathione S-Transferase)
5.	Dichloroacetic Acid
6.	Acids
7.	maleic acid (maleate)
8.	fumarylacetoacetase (fumarylacetoacetate hydrolase)