|1.||Murphy, Timothy F: 2 articles (12/2015 - 01/2011)|
|2.||Sethi, Sanjay: 2 articles (12/2015 - 01/2011)|
|3.||Kirkham, Charmaine: 2 articles (12/2015 - 01/2011)|
|4.||Liberati, David M: 2 articles (05/2009 - 10/2004)|
|5.||Diebel, Lawrence N: 2 articles (05/2009 - 10/2004)|
|6.||Vitovski, Srdjan: 2 articles (06/2007 - 04/2002)|
|7.||Sayers, Jon R: 2 articles (06/2007 - 04/2002)|
|8.||Kong, Yong: 1 article (12/2015)|
|9.||Pettigrew, Melinda M: 1 article (12/2015)|
|10.||Jones, Megan M: 1 article (12/2015)|
06/01/1999 - "gonorrhoeae does not require IgA1 protease production to cause experimental urethritis in males."
01/01/2011 - "Studies with isogenic mutants have improved our understanding of the requirements for gonococcal LOS structures, pili, opacity proteins, IgA1 protease, and the ability of infecting organisms to obtain iron from human transferrin and lactoferrin during uncomplicated urethritis. "
06/01/2007 - "Bacterial isolates show wide variability in IgA1 protease activity, and those isolated from patients with clinical infection possess the highest levels of activity. "
02/01/2000 - "gonorrhoeae infection of T84 monolayers, grown on a solid substrate or polarized on semiporous membranes, also results in IgA1 protease-mediated reduction of LAMP1. "
06/01/1999 - "A Neisseria gonorrhoeae immunoglobulin A1 protease mutant is infectious in the human challenge model of urethral infection."
10/01/1998 - "We conclude that neisseria infection results in multiple changes to the lysosomes of infected epithelial cells and that these changes are likely an indirect result of IgA1 protease-mediated cleavage of LAMP1."
03/01/1998 - "Yet the presence of this enzyme is, if at all, only a minor decisive factor for the induction of symptomatic infections of the upper respiratory tract by IgA1 protease-positive bacteria."
10/01/2004 - "Expression of IgA protease activity might be important in the development and subsequent outcome of gram-negative pneumonia in the patient in the surgical intensive care unit."
05/01/2009 - "Previous studies have demonstrated that gram-negative but not gram-positive isolates from patients with nosocomial pneumonia have IgA protease activity that contributes to the development of infection. "
09/01/1990 - "pneumoniae is a respiratory pathogen for several species of animals, we sought to determine whether isolates of this organism from animals with pneumococcal infection, including fatal diplococcal pneumonia, produced an IgA protease. "
07/01/1984 - "Haemophilus pleuropneumoniae, the etiological agent of porcine contagious pneumonia, was examined for the ability to produce an immunoglobulin A (IgA) protease specific for porcine IgA. "
10/18/1999 - "In particular, IgA1 protease may represent a key virulence determinant of bacterial meningitis."
05/01/1996 - "Although it has been known since 1979 that IgA1 protease is produced by the three leading causes of bacterial meningitis in addition to important urogenital pathogens and some members of the oropharyngeal flora, the exact role of this enzyme in bacterial pathogenesis is still incompletely understood owing to lack of a satisfactory animal model. "
01/01/2002 - "These findings support the significance of IgA1 protease as a virulence determinant of bacterial meningitis and its function as a dominant proinflammatory T-cell antigen."
09/01/1995 - "Pathogenic Neisseria species, the causative agents of gonorrhoea and bacterial meningitis, encode a family of polymorphic exo-proteins which are autoproteolytically processed into several distinct extracellular components, including an IgA1 protease and an alpha-protein. "
03/01/1981 - "In samples from initial and mature dental plaque 38 to 40% of streptococcal isolates produced IgA1 protease. "
03/01/1981 - "A collection of 459 streptococcal strains, including reference strains of Streptococcus species, and fresh isolates from human dental plaque and buccal and pharyngeal mucosa were identified by biochemical means and were examined for IgA1 protease production. "
06/01/1991 - "Immunoglobulin A1 (IgA1) protease-producing streptococci were primarily isolated from initial dental plaque and from the buccal mucosa. "
05/01/1975 - "IgA protease is a proteolytic enzyme found in whole human saliva and in dental plaque that cleaves both secretory and myeloma IgA of human origin to yield intact Fabalpha and Fcalpha fragments. "
09/01/1993 - "Similar proportions of immunoglobulin A1 (IgA1) protease-producing streptococci in initial dental plaque of selectively IgA-deficient and normal individuals."
|1.||Transferrin (beta 2 Transferrin)
|5.||Immunoglobulin A (IgA)
|8.||Proteins (Proteins, Gene)
|9.||Membrane Proteins (Integral Membrane Proteins)
|1.||Intensive Care (Surgical Intensive Care)