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hexadecanal dehydrogenase (acylating) (fatty acyl-CoA reductase)

Also Known As:

fatty acyl-CoA reductase; acyl-CoA reductase; fatty acyl-coenzyme A reductase

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxidoreductases Acting on Aldehyde or Oxo Group Donors
      - Aldehyde Oxidoreductases: 1
        hexadecanal dehydrogenase (acylating): 12

Experts

1.	Kihara, Akio: 1 article (01/2022)
2.	Otsuka, Kento: 1 article (01/2022)
3.	Sawai-Ogawa, Megumi: 1 article (01/2022)
4.	Arrieta, Adrian: 1 article (01/2021)
5.	Blackwood, Erik A: 1 article (01/2021)
6.	Glembotski, Christopher C: 1 article (01/2021)
7.	MacDonnell, Lauren: 1 article (01/2021)
8.	Marsh, Kayleigh G: 1 article (01/2021)
9.	Thuerauf, Donna J: 1 article (01/2021)
10.	Chen, Quanjia: 1 article (10/2019)

Related Diseases

1.	Male Infertility (Male Sterility) 10/16/2019 - "In this study, we identified DEGs associated with reactive oxygen species (ROS), peroxisomes, aldehyde dehydrogenases (ALDH), cytochrome oxidase subunit VI, and cytochrome P450, and DEGs associated with tapetum development, Jojoba acyl-CoA reductase-related male sterility protein, basic helix-loop-helix (bHLH) and MYB transcription factors. "
2.	Neoplasms (Cancer) 09/01/1979 - "Acyl-CoA reductase specificity and synthesis of wax esters in mouse preputial gland tumors." 09/01/1979 - "Acyl-CoA reductase specificity and synthesis of wax esters in mouse preputial gland tumors." 08/11/1980 - "We have compared the activities of three enzymes (acyl-CoA reductase, fatty alcohol:NAD+ oxidoreductase, and alkyl synthase) involved in the metabolism of ether lipids in rat liver and two tumors that contained various levels of ether lipids. "
3.	Microcephaly 01/01/2015 - "Investigators from Erlangen, Germany; Calgary, CA; and Kafranbel, Syria, identified mutations in the gene, fatty acyl-CoA reductase 1 (FAR1) deficiency, adding to three other genes involved in plasmalogen biosynthesis, in two families affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity. " 11/06/2014 - "Here, we report the identification of mutations in another gene in plasmalogen biosynthesis, fatty acyl-CoA reductase 1 (FAR1), in two families affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity. "
4.	Intellectual Disability (Idiocy) 11/06/2014 - "A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency." 01/01/2015 - "Investigators from Erlangen, Germany; Calgary, CA; and Kafranbel, Syria, identified mutations in the gene, fatty acyl-CoA reductase 1 (FAR1) deficiency, adding to three other genes involved in plasmalogen biosynthesis, in two families affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity. " 11/06/2014 - "Here, we report the identification of mutations in another gene in plasmalogen biosynthesis, fatty acyl-CoA reductase 1 (FAR1), in two families affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity. "
5.	Epilepsy (Aura) 11/06/2014 - "A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency." 01/01/2015 - "Investigators from Erlangen, Germany; Calgary, CA; and Kafranbel, Syria, identified mutations in the gene, fatty acyl-CoA reductase 1 (FAR1) deficiency, adding to three other genes involved in plasmalogen biosynthesis, in two families affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity. " 11/06/2014 - "Here, we report the identification of mutations in another gene in plasmalogen biosynthesis, fatty acyl-CoA reductase 1 (FAR1), in two families affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Reactive Oxygen Species (Oxygen Radicals)
3.	Transcription Factors (Transcription Factor)
4.	Oxidoreductases (Dehydrogenase)
5.	Cytochrome P-450 Enzyme System (Cytochrome P450)
6.	Electron Transport Complex IV (Cytochrome c Oxidase)
7.	Aldehydes
8.	Plasmalogens
9.	Lipids
10.	RNA Helicases (RNA Helicase)