glycoprotein containing 20% carbohydrate which moves as a beta(1) globulin on electrophoresis; MW 36,000; TFPI-2 is an important regulator of the extrinsic pathway of blood coagulation; a factor VIIA antagonist; present in placenta, maternal serum in late pregnancy, liver, heart, pancreas, and other tissues; a serine protease inhibitor; GenBank L27624 (human); REfSeq NM_006528 (human), NM_009364 (mouse)
Also Known As:
PP5; MSPI protein; PP5 protein, human; PP5 protein, mouse; Placental protein 5, human; TFPI-2; TFPI2 protein, human; Tfpi2 protein, mouse; matrix-associated serine protease inhibitor; placenta-specific protein 5; placental protein 5; tissue factor pathway inhibitor 2 protein, human; tissue factor pathway inhibitor 2 protein, mouse; tissue factory pathway inhibitor-2