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4-nitrocatechol sulfate
RN given refers to 2-sulfate moiety locant
Also Known As:
2-hydroxy-5-nitrophenyl sulfate; 4-nitrocatechol sulfate, dipotassium salt; 4-nitrocatechol sulfate, monopotassium salt; p-nitrocatechol sulfate; para-nitrocatechol sulfate; 4-nitro-1,2-benzenediol, 2-(hydrogen sulfate)
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Phenols: 677
Catechols: 121
4-nitrocatechol sulfate: 3
Related Diseases
1.
Neoplasms (Cancer)
01/01/1988 - "
The time course of the arylsulfatase A reaction with 4-nitrocatechol sulfate was not linear in normal individuals, while it was linear in 90% of patients with urothelial tumors.
"
10/01/1980 - "
The tumor B1 enzyme was demonstrated to be most probably an isoenzyme of arylsulfatase B, since this unusual enzyme was indistinguishable from arylsulfatase B in terms of Ag+ inhibition; its kinetic parameters of Km for p-nitrocatechol sulfate, which was 2.9 mM with B1; optimum pH of 6.3 for B1; heat stability; and substrate specificity for three synthetic and two physiological substrates.
"
2.
Metachromatic Leukodystrophy (Sulfatide Lipidosis)
10/31/1991 - "
The arylsulfatase A defect in metachromatic leukodystrophy cells could be demonstrated on focused fractions even using the artificial substrates, para-nitrocatechol sulfate and 4-methylumbelliferyl sulfate.
"
10/31/1991 - "
Lymphoid cells derived from patients with metachromatic leukodystrophy showed a severe deficiency in cerebroside sulfatase activity, as measured using radiolabelled sulfatide, but some residual activity of arylsulfatase A when measured with the chromogenic substrate, para-nitrocatechol sulfate.
"
Related Drugs and Biologics
1.
Cerebroside-Sulfatase (Arylsulfatase A)
2.
N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B)
3.
Sulfoglycosphingolipids (Sulfatides)
4.
Isoenzymes
5.
Enzymes
6.
Chromogenic Compounds
7.
4-methylumbelliferyl sulfate