|1.||Newman, Robert A: 9 articles (04/2015 - 01/2006)|
|2.||Yang, Peiying: 7 articles (04/2015 - 01/2006)|
|3.||Cartwright, Carrie: 5 articles (04/2015 - 01/2006)|
|4.||Newman, R A: 4 articles (08/2001 - 07/2000)|
|5.||Addington, Crandell: 3 articles (04/2015 - 01/2006)|
|6.||Chan, Diana: 3 articles (08/2009 - 01/2006)|
|7.||Dixon, Susan: 3 articles (08/2009 - 01/2006)|
|8.||Johansen, Mary: 2 articles (11/2011 - 12/2007)|
|9.||Ho, Dah H: 2 articles (01/2010 - 01/2008)|
|10.||Lin, Yun: 2 articles (01/2010 - 01/2008)|
01/01/2013 - "Oleandrin, the principle cardiac glycoside (CG) in Anvirzel™ has been shown to exhibit anti-cancer properties but its efficacy against HIV is unknown. "
01/01/2015 - "Recently, several studies have reported the selective antitumor effect of oleandrin on various tumor cells. "
07/01/2013 - "The present review focuses the applicability of oleandrin in cancer treatment and concerned future perspective in the area. "
07/01/2013 - "Retraction note: Oleandrin-mediated expression of Fas potentiates apoptosis in tumor cells."
01/01/2008 - "While human tumor cells are very sensitive to growth inhibition by oleandrin, murine tumor cells are extremely resistant. "
|2.||Prostatic Neoplasms (Prostate Cancer)
08/15/2001 - "In continuing research on the antitumor activity of this novel plant extract, the relative abilities of oleandrin and oleandrigenin to inhibit FGF-2 export from two human prostate cancer cell lines, DU145 and PC3, were examined. "
08/15/2001 - "Inhibition of export of fibroblast growth factor-2 (FGF-2) from the prostate cancer cell lines PC3 and DU145 by Anvirzel and its cardiac glycoside component, oleandrin."
08/15/2001 - "These results demonstrate that Anvirzel, like oleandrin, inhibited FGF-2 export in vitro from PC3 and DU145 prostate cancer cells in a concentration- and time-dependent fashion and may, therefore, contribute to the antitumor activity of this novel treatment for cancer."
07/15/2000 - "Here, we report that the cardiac glycosides oleandrin, ouabain, and digoxin induce apoptosis in androgen-independent human prostate cancer cell lines in vitro. "
05/01/2008 - "The use of cardenolides like ouabain, digitoxin, or oleandrin has been reported previously many times as a means of potentially combating human refractory prostate cancer by inducing apoptosis through an increase in intracellular calcium concentrations. "
|3.||Pancreatic Neoplasms (Pancreatic Cancer)
04/01/2015 - "Here, we report the antitumor efficacy of PBI-05204, a supercritical C0₂ extract of Nerium oleander containing oleandrin, in a human pancreatic cancer Panc-1 orthotopic model. "
12/01/2007 - "The data provide insight into the mechanisms and role of a potent, lipid-soluble cardiac glycoside (oleandrin) in control of human pancreatic cancer proliferation."
09/01/2015 - "An unusual case of oleandrin poisoning suggesting its possible antiarrhythmic activity."
01/01/2010 - "Oleandrin was detected in the blood sample at a concentration of 14.7 ng/ml. Following a review of the literature, this is the first case of oleander poisoning in which the patient recovered with only conservative treatment. "
08/06/2008 - "A fatal case of oleandrin poisoning."
11/01/2006 - "Unexpectedly dangerous escargot stew: oleandrin poisoning through the alimentary chain."
07/01/2005 - "Comparison with previous reports indicates that single compound analysis only permits a toxicological assessment for oleander poisoning and results in the proposal to classify an oleandrin level between 1.0 and 2.0 ng/ml as toxic blood plasma/serum concentration."
|5.||Melanoma (Melanoma, Malignant)
01/01/2008 - "Determinants of human and mouse melanoma cell sensitivities to oleandrin."
01/01/2006 - "Oleandrin-mediated oxidative stress in human melanoma cells."
01/01/2006 - "We now demonstrate that incubation of human malignant melanoma BRO cells with oleandrin results in a time-dependent formation of reactive oxygen species (ROS). "
|2.||Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)
|4.||Adenosine Triphosphatases (ATPase)
|6.||Ouabain (G Strophanthin)
|8.||NF-kappa B (NF-kB)
|10.||Protein Subunits (Protein Subunit)