|1.||Akao, Yukihiro: 9 articles (09/2015 - 10/2004)|
|2.||Iinuma, Munekazu: 8 articles (01/2012 - 10/2004)|
|3.||Suksamrarn, Sunit: 5 articles (01/2015 - 04/2011)|
|4.||Yang, Ling-Ling: 4 articles (09/2013 - 02/2008)|
|5.||Watanapokasin, Ramida: 4 articles (12/2012 - 04/2011)|
|6.||Nozawa, Yoshinori: 4 articles (03/2008 - 11/2004)|
|7.||Chin, Young-Won: 3 articles (09/2015 - 11/2012)|
|8.||Clinton, Steven K: 3 articles (01/2015 - 02/2013)|
|9.||Failla, Mark L: 3 articles (01/2015 - 02/2013)|
|10.||Thomas-Ahner, Jennifer M: 3 articles (01/2015 - 02/2013)|
|1.||Pancreatic Neoplasms (Pancreatic Cancer)
01/01/2014 - "Furthermore, we found that α -mangostin suppressed the activity of the PI3K/Akt pathway in pancreatic cancer cells as demonstrated by the reduction of the Akt phosphorylation by α -mangostin. "
01/01/2014 - "Treatment of pancreatic cancer BxPc-3 and Panc-1 cells with α -mangostin resulted in loss of cell viability, accompanied by enhanced cell apoptosis, cell cycle arrest at G1 phase, and decrease of cyclin-D1. "
01/01/2014 - "Here, we report that α -mangostin suppressed the viability and epithelial-mesenchymal transition (EMT) of pancreatic cancer cells through inhibition of the PI3K/Akt pathway. "
01/01/2014 - "α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway."
01/01/2014 - "Our results suggest that α -mangostin may be potentially used as a novel adjuvant therapy or complementary alternative medicine for the management of pancreatic cancers. "
05/01/2014 - "α-Mangostin significantly and dose-dependently reduced formation of ROS in hypoxia-treated REC. "
05/28/2014 - "Therefore, α-mangostin may be beneficial in preventing hypoxia-induced pancreatic cancer progression. "
05/28/2014 - "α-Mangostin suppresses hypoxia-induced PSC activation and pancreatic cancer cell invasion through the inhibition of HIF-1α stabilization and GLI1 expression. "
05/28/2014 - "α-Mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion."
05/28/2014 - "Recent advances indicating a key role of microenvironment for tumor progression, we investigated the role of PSCs and hypoxia in pancreatic cancer aggressiveness, and examined the potential protective effect of α-mangostin on hypoxia-driven pancreatic cancer progression. "
02/01/2012 - "We then performed an in vivo animal study to evaluate the ability of α-mangostin to suppress tumor growth. "
01/01/2011 - "Recently, the compound α-mangostin, which is isolated from the pericarp of the fruit, was shown to induce cell death in various types of cancer cells in in vitro studies. "
10/10/2014 - "Next, we evaluated α-Mangostin for microsomal stability, pharmacokinetic parameters, and anti-cancer activity in nude mice. "
05/01/2014 - "α-Mangostin, a component of mangosteen (Garcinia mangostana Linn), has been shown to have an anti-oxidant property in pathological conditions involving angiogenesis such as cancer. "
01/01/2014 - "α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and Hsp70 protein modulation in vitro, and tumor reduction in vivo."
|4.||Breast Neoplasms (Breast Cancer)
04/01/2014 - "In this study, we evaluated the effects of α-mangostin on cell growth inhibition and induction of apoptosis in MCF-7 ERα-positive human breast cancer cells. "
01/01/2012 - "In this study, we investigated the influence of α-mangostin on apoptosis and cell cycle in the human breast cancer cell line MDA-MB231 (carrying a p53 mutation, and HER2, ER, and PgR negative) in order to elucidate its anticancer mechanisms. "
04/01/2014 - "Therefore, α-mangostin may be used to prevent and treat of ER-positive breast cancer. "
04/01/2014 - "These results suggest that ERα is required for α-mangostin-induced growth inhibition and apoptosis in human breast cancer cells. "
01/01/2014 - "We evaluated the cytotoxicity of alpha-mangostin in human breast cancer MCF-7 and MDA-MB-231 cells. "
|5.||Melanoma (Melanoma, Malignant)
01/01/2014 - "In studies of anticancer abilities, the release of 2.0 μg/ml α-mangostin from the BC films could suppress the growth of B16F10 melanoma (approximately 31% survival). "
08/08/2014 - "Inhibition of cell proliferation, migration and invasion of B16-F10 melanoma cells by α-mangostin."
01/01/2013 - "We previously demonstrated that α-mangostin, γ-mangostin, and 8-deoxygartanin have significant cytotoxic effects on human melanoma SK-MEL-28 cell line. "
09/01/2012 - "This study aimed at investigating the anti-invasive activities of α-mangostin on human melanoma SK-MEL-28 and squamous cell carcinoma A-431 cell lines. "
01/01/2014 - "With the release of α-mangostin at greater than 17.4-18.4 μg/ml, less than 15 and 5% survival of B16F10 melanoma and MCF-7 breast cancer cells, respectively, was observed."
|4.||Matrix Metalloproteinase 2 (Gelatinase A)
|6.||Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)
|7.||Matrix Metalloproteinase 9 (Gelatinase B)
|10.||epigallocatechin gallate (epigallocatechin-3-gallate)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Complementary Therapies (Alternative Medicine)
|3.||Prostatectomy (Retropubic Prostatectomy)
|4.||Photochemotherapy (Photodynamic Therapy)
|5.||Traditional Medicine (Folk Remedies)