|1.||Sacks, Harry: 7 articles (07/2011 - 05/2005)|
|2.||Lieberman, Phil: 6 articles (04/2015 - 04/2005)|
|3.||Wheeler, William: 6 articles (07/2011 - 09/2007)|
|4.||Price, David: 5 articles (04/2015 - 05/2012)|
|5.||Bernstein, Jonathan A: 5 articles (04/2015 - 10/2007)|
|6.||Munzel, Ullrich: 5 articles (03/2014 - 01/2006)|
|7.||Bachert, Claus: 4 articles (04/2015 - 11/2011)|
|8.||Bernstein, Jonathan: 4 articles (04/2015 - 05/2005)|
|9.||Berger, William E: 4 articles (03/2014 - 08/2003)|
|10.||Lieberman, P: 4 articles (01/2013 - 01/2001)|
07/01/1987 - "Azelastine, already proven effective in allergic rhinitis, has a bronchodilator effect at doses that do not produce intolerable side effects."
07/01/2000 - "The analysis of the Rhinitis Severity Score showed significant improvement only of rhinorrhea in the azelastine group (P = .03). "
04/01/2015 - "Other agents effective in treating nonallergic rhinitis (NAR) such as azelastine have been demonstrated to exhibit TRPV1 channel activity through the modulation of Ca(2+) signaling on sensory neurons and in nasal epithelial cells. "
03/01/1997 - "Azelastine is a topical antihistamine, clinically demonstrated to be effective in allergic rhinitis. "
02/01/1997 - "Azelastine is a selective H1-receptor antagonist, which has previously been demonstrated to be effective in the treatment of allergic rhinitis. "
|2.||Seasonal Allergic Rhinitis (Hay Fever)
04/01/1994 - "Azelastine nasal spray, administered either once or twice daily, was effective in treating the symptoms of seasonal allergic rhinitis and demonstrated a rapid onset of action with a duration of response lasting 12 to 24 hours."
01/01/2013 - "Azelastine has been shown to be effective against seasonal allergic rhinitis (SAR). "
06/01/1999 - "Three multicenter, randomized, double-blind studies were conducted to determine whether patients with moderate-to-severe symptoms of seasonal allergic rhinitis who had responded inadequately to monotherapy with either an oral antihistamine or an intranasal corticosteroid, and who were candidates for combination therapy with both an oral antihistamine and an intranasal corticosteroid, could be effectively treated with azelastine nasal spray monotherapy. "
03/01/1987 - "In addition, azelastine has been shown to have an effect on the upper airways by effective symptom relief in patients with seasonal allergic rhinitis; furthermore, azelastine affords protection against exercise and allergen provocation."
07/01/1999 - "Azelastine hydrochloride is a nasally administered antihistamine that is effective and safe for the treatment of perennial and seasonal allergic rhinitis. "
|3.||Asthma (Bronchial Asthma)
05/01/1989 - "Azelastine was more effective in improving respiratory function (forced expiratory flow in 1 s and peak expiratory flow rate) when given in the once daily regimen, whereas clinical measures (number of weekly asthma attacks) were most improved by twice daily dosing. "
11/01/1997 - "Compared with the placebo-treated group, the azelastine-treated group exhibited significant improvement of asthma symptoms (p<0.01), PEF (p<0.01), PEF diurnal variation (p<0.001), excluding forced expiratory volume in 1 s or airway responsiveness. "
11/01/1990 - "Thus, azelastine was safely tolerated over one year and might be effective in intrinsic asthma."
11/01/1988 - "A study of the clinical efficacy of azelastine in patients with extrinsic asthma, and its effect on airway responsiveness."
03/01/1990 - "Evaluation of the safety and efficacy of multiple doses of azelastine to adult patients with bronchial asthma over time."
04/01/2003 - "Both drugs were found to be equally effective in relieving itching [18 (58.1%) in the MMC group versus 18 (52.9%) in the azelastine group; not significant]. "
01/01/2003 - "Azelastine significantly improved itching and conjunctival redness compared to placebo (p < 0.001) with global tolerability that was not substantially different from placebo. "
01/01/2003 - "Azelastine significantly improved itching and conjunctival redness versus placebo (p < 0.001). "
02/01/1998 - "In all 230 evaluable patients with moderate to severe itching, azelastine caused an overall significant improvement in comparison to placebo (P = 0.02), with significance also for pruritus (P = 0.01 after 1 week and P = 0.02 after 2 weeks). "
01/01/2003 - "Itching and redness further improved at Day 42 (score improvement > or = 2 in 95% with azelastine versus 33% placebo) and completely resolved for 47% azelastine patients (versus 10% placebo). "
|5.||Perennial Allergic Rhinitis
03/01/1994 - "Results indicate that with the dose used azelastine nasal spray is an effective treatment for both seasonal and perennial allergic rhinitis."
09/01/1988 - "Efficacy of azelastine in perennial allergic rhinitis: clinical and rhinomanometric evaluation."
02/14/1997 - "One hundred and twenty five children (median age 8.71 years) suffering from perennial allergic rhinitis were treated in a randomized, double-blind, parallel group study comparing azelastine nasal spray 0.14 mg/nostril twice daily (0.56 mg/day) and placebo nasal spray. "
08/01/1994 - "The objective of this 8-week double-blind trial was to evaluate further azelastine's efficacy and safety in improving the symptoms of perennial allergic rhinitis over a prolonged period of treatment. "
07/01/2000 - "We recruited 24 subjects with perennial allergic rhinitis and randomized them in a double-blinded, crossover fashion, to receive placebo or azelastine two sprays BID, using Balaam's design. "
|3.||Histamine Antagonists (Antihistamines)
|8.||Histamine (Histamine Dihydrochloride)
|10.||mometasone furoate (mometasone)
|4.||Phototherapy (Light Therapy)
|5.||Drug Therapy (Chemotherapy)