|1.||Pillar, Giora: 1 article (06/2015)|
|2.||Oliven, Arie: 1 article (06/2015)|
|3.||Dotan, Yaniv: 1 article (06/2015)|
|4.||Schwartz, Alan R: 1 article (06/2015)|
|5.||Hosono, T: 1 article (10/2014)|
|6.||Kohda, Y: 1 article (10/2014)|
|7.||Homma, M: 1 article (10/2014)|
|8.||Satoh, M: 1 article (10/2014)|
|9.||Ma, Cui: 1 article (10/2013)|
|10.||Wu, Wenyuan: 1 article (10/2013)|
|1.||Sleep Initiation and Maintenance Disorders (Insomnia)
10/01/2013 - "Brotizolam is effective and safe in relieving the symptoms of insomnia."
06/01/1985 - "Fifty-nine outpatients with insomnia were treated in a 3-week study to assess the safety and efficacy of a new triazolothienodiazepine with a short t1/2, brotizolam. "
10/01/2013 - "A randomized, double-blind, double-dummy, multicenter, controlled trial on brotizolam intervention in outpatients with insomnia."
01/01/1983 - "Brotizolam and chronic insomnia: a multi-centre study."
10/01/2013 - "To investigate the efficacy and safety of brotizolam in outpatients with insomnia. "
02/01/1986 - "In both trials, brotizolam produced significant increases in self-rated perceptions of sedation, fatigue, feeling 'spaced-out', and thinking slowed down. "
02/01/1986 - "Brotizolam produced self-rated perceptions of sedation and fatigue during 4-6 h after dosage, but objective impairment of psychomotor performance was minimal. "
06/01/2012 - "The present study describes activity pattern changes after a single dose of brotizolam in elderly patients with dementia. "
06/01/2012 - "Use of brotizolam in elderly patients with dementia, especially in advanced stages, calls for closer attention and longer observation periods."
06/01/2012 - "Findings showed changes in activity levels and reversed active/resting phases after a single dose of brotizolam in elderly patients with dementia. "
06/01/2012 - "Around-the-clock movements of dementia patients who were administered a single dose of brotizolam were recorded by the integrated circuit tag monitoring system during a 4-week baseline and 7-day peri-administration period. "
06/01/2012 - "Changes in activity patterns after the oral administration of brotizolam in institutionalized elderly patients with dementia."
08/22/2007 - "L-Glutamic acid attenuated retrograde amnesia but did not affect anterograde amnesia induced by brotizolam. "
08/22/2007 - "Norharmane reversed anterograde amnesia induced by brotizolam and did not reverse retrograde amnesia induced by it. "
08/22/2007 - "Triazodiazepines such as alprazolam, triazolam and brotizolam produce both anterograde and retrograde amnesia. "
08/22/2007 - "Sustained inhibition of brotizolam induced anterograde amnesia by norharmane and retrograde amnesia by L-glutamic acid in mice."
08/22/2007 - "The present study was designed to investigate the effect of norharmane (benzodiazepine receptor inverse agonist) and L-glutamic acid (glutamate receptor agonist) on brotizolam induced anterograde and retrograde amnesia using Morris water maze task in mice. "
08/01/1999 - "Thus, in addition to its long-lasting suppression of motor seizures in rats, brotizolam does not alter the time course of recovery from refractoriness of the neurons that mediate brain-stimulation reward in the lateral preoptic area."
08/01/1999 - "Control of motor seizures by brotizolam with maintenance of stable refractory periods for self-stimulation."
03/01/1986 - "Brotizolam prevented audiogenic seizures in mice, seizures provoked by electroshock in rats and inhibited convulsions elicited by electrical stimulation in the limbic system of cats. "
12/01/1984 - "When motor activities and pentetrazol-induced convulsions were observed as indices of tolerance for brotizolam, tolerance was not developed by repeated administration of brotizolam up to 14 days. "
12/01/1984 - "Brotizolam inhibited spontaneous motor activities; performances in the rotarod test, staircase test, and maximal electroshock seizure test; and pentetrazol- or bemegride-induced convulsion. "
|6.||Glutamic Acid (Glutamate)
|7.||Glutamate Receptors (Glutamate Receptor)
|8.||GABA-A Receptors (GABA(A) Receptor)