1- (2- hydroxyethyl)- 2- hydroxymethyl- 5- nitroimidazole

human urinary metabolite of metronidazole; structure

Also Known As:

2-(hydroxymethyl)-5-nitro-1H-imidazole-1-ethanol; 2-hydroxymethylmetronidazole; 2-hydroxymetronidazole; 20396 RP; RP 20396; RP-20396

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Colitis 01/01/2023 - "Hepatic microsomal incubation with metronidazole revealed that the production rate of 2-hydroxymetronidazole was inhibited, suggestive of a diminished hydroxylation reaction upon colitis. "
2.	Chromosome Aberrations (Chromosome Abnormalities) 07/01/1979 - "The antiprotozoan agent metronidazole (1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole) and two of its major human urinary excretion products, 2-methyl-5-nitromidazole-1-yl acetic acid and 1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole were tested for genotoxic activity in human lymphocytes in vitro by analysis of chromosome aberrations, sister-chromatid exchanges and DNA-repair synthesis. "