cytosol non-specific dipeptidase (glycyl-glycine dipeptidase)

also referred to as peptidase A (see synonym to penicillopepsin, EC 3.4.23.20)

Also Known As:

glycyl-glycine dipeptidase; glycyl-leucine dipeptidase; Gly-Leu dipeptide peptidase; dipeptide hydrolase; glycyl-L-leucine hydrolase; glycylglycine dipeptidase; glycylleucine dipeptidase

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Exopeptidases: 68
        Dipeptidases: 22
        cytosol non-specific dipeptidase: 4

Related Diseases

1.	Malnutrition (Nutritional Deficiencies) 11/01/1971 - "Undernutrition and intestinal dipeptide hydrolase activity in the rat."
2.	Lung Neoplasms (Lung Cancer) 07/01/1988 - "Forty-two patients with lung cancer and 72 healthy subjects were studied in order to determine a possible relationship between serum zinc and angiotensin-converting enzyme (ACE), a peptidyl dipeptide hydrolase. "
3.	Inflammation (Inflammations) 08/30/1996 - "Angiotensin-converting enzyme (ACE; EN 3.4.15.1) is a peptidyl dipeptide hydrolase that removes the carboxyl terminal His-Leu from angiotensin I to produce the octapeptide angiotensin II. In addition, ACE inactivates bradykinin, a vasodilator peptide/mediator of inflammation, as well as substance P, enkephalins and endorphins. "
4.	Crohn Disease (Crohn's Disease) 04/01/1971 - "Eight patients, four of whom had Crohn's disease, were found to have a marked reduction in the activity of glycylglycine dipeptidase and, to a lesser extent, of the other two hydrolases. "

Related Drugs and Biologics

1.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
2.	Zinc
3.	Vasodilator Agents (Vasodilators)
4.	Substance P
5.	Peptides (Polypeptides)
6.	Hydrolases
7.	Enkephalins
8.	Endorphins
9.	Bradykinin
10.	Angiotensin II