|1.||Malvagia, Sabrina: 4 articles (01/2012 - 01/2008)|
|2.||la Marca, Giancarlo: 4 articles (01/2012 - 01/2008)|
|3.||Pasquini, Elisabetta: 3 articles (01/2011 - 01/2008)|
|4.||Zammarchi, Enrico: 3 articles (01/2011 - 01/2008)|
|5.||Adam, Barbara W: 2 articles (09/2014 - 12/2009)|
|6.||Matern, Dietrich: 2 articles (09/2014 - 05/2006)|
|7.||Holme, Elisabeth: 2 articles (01/2013 - 01/2009)|
|8.||Wang, Yu: 2 articles (12/2012 - 02/2012)|
|9.||Qiu, Wen-juan: 2 articles (12/2012 - 02/2012)|
|10.||Ye, Jun: 2 articles (12/2012 - 02/2012)|
06/01/2011 - "In 2 years, the New York newborn screening program has analyzed approximately 500,000 samples for succinylacetone (SUAC), the biomarker for Tyrosinemia, type I. There have been five screen-positive results. "
01/01/2016 - "Succinylacetone (SA) is used for the diagnosis and monitoring of patients with tyrosinemia type I (Tyr I). "
09/01/2014 - "Succinylacetone as primary marker to detect tyrosinemia type I in newborns and its measurement by newborn screening programs."
08/16/2012 - "Both hematocrit and blood volume have effect on analysis of succinylacetone in dried blood spots, the effect of hematocrit is more significant, due to hematocrit level of majority Type I tyrosinemia patients is low, diagnoses may be missed by using dried blood spots to analysis."
02/01/2012 - "A total of 190 patients suspected of having tyrosinemia, were tested by tandem mass spectrometry for measurement of the level of succinylacetone in the blood, and detected by gas chromatography-mass spectrometry for measurement of the level of succinylacetone and organic acid in the urine. "
01/01/2002 - "Liver function tests and succinylacetone levels were completely corrected with this regimen and cancer-free survival was improved when compared to historical controls. "
11/01/1987 - "Succinylacetone is a seven-carbon organic ketoacid that we have previously shown to inhibit tumor allograft rejection as well as the primary antibody response to sheep erythrocytes in rats. "
|3.||Body Weight (Weight, Body)
|4.||Fanconi Syndrome (Syndrome, Fanconi)
07/01/1992 - "3. We conclude that the physiological alterations produced in normal rat renal tubules by succinylacetone provide the basis for the study of the biochemical changes underlying the human renal Fanconi syndrome."
07/01/1992 - "Physiological basis for an animal model of the renal Fanconi syndrome: use of succinylacetone in the rat."
04/01/1991 - "Succinylacetone effects on renal tubular phosphate metabolism: a model for experimental renal Fanconi syndrome."
10/24/1985 - "It is concluded that succinylacetone may be a useful probe in elucidation of the biochemical mechanism underlying the human Fanconi syndrome."
02/01/1987 - "Infants with hereditary tyrosinemia also have a renal Fanconi syndrome and excrete succinylacetone (SA). "
|5.||Acute Erythroblastic Leukemia (Erythroleukemia)
03/01/1981 - "Uptake of hematin and growth of malignant murine erythroleukemia cells depleted of endogenous heme by succinylacetone."
06/27/1979 - "Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme content and delta-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells."
11/05/2004 - "To investigate the involvement of Bach1 in the heme-dependent regulation of the expression of the alpha-globin gene, human erythroleukemia K562 cells were cultured with succinylacetone (SA), a heme biosynthetic inhibitor, and the level of alpha-globin mRNA was examined. "
02/13/2004 - "To investigate the involvement of Bach1 in the heme-dependent regulation of the expression of the beta-globin gene, mouse erythroleukemia (MEL) cells were cultured with succinylacetone (SA), a specific inhibitor of heme biosynthesis, and the level of beta-globin mRNA was examined. "
10/01/1984 - "Effects of succinylacetone on dimethylsulfoxide-mediated induction of heme pathway enzymes in mouse friend virus-transformed erythroleukemia cells."
|6.||Aminolevulinic Acid (Levulan)
|7.||Porphobilinogen Synthase (delta-Aminolevulinate Dehydratase)
|1.||Homologous Transplantation (Allograft)