01/01/1988 - "Cytogenetic studies on rat thymic lymphomas induced by N-propyl-N-nitrosourea."
05/01/1999 - "Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis."
07/15/1997 - "Thymic lymphomas (FTLs) induced by the chemical carcinogen 1-propyl-1-nitrosourea (PNU) in F344 rats showed deviated overexpression of TCR-beta, TCR-gamma, CD4, and CD8. "
07/01/1995 - "To clarify the linkage between Hbb and Tls-1 (thymic lymphoma susceptible-1) loci and to investigate other loci concerned in thymic lymphomagenesis, the BUF/Mna rat, which is highly sensitive to the lymphomagenic activity of N-propyl-N-nitrosourea (PNU), the WKY/NCrj rat, reported to be resistant, and their cross offspring were subjected to genetic analysis. "
07/01/1995 - "Genetic regulation of development of thymic lymphomas induced by N-propyl-N-nitrosourea in the rat."
10/01/1982 - "Continuous administration of either 400 ppm or 100 ppm 1-propyl-1-nitrosourea (PNU) in drinking water to Syrian golden hamsters, from 11 weeks of age, induced tumors of the spleen, forestomach, duodenum, and vagina. "
10/01/1982 - "Vascular tumors of the spleen and other neoplasms induced in Syrian golden hamsters by 1-propyl-1-nitrosourea."
02/01/1976 - "Induction of tumors in female Donryu rats by a single administration of 1-propyl-1-nitrosourea."
02/01/1976 - "Mammary and subcutaneous tumors were found in some rats given a subcutaneous injection of 1-propyl-1-nitrosourea."
01/01/1988 - "Induction of lung tumors and peritoneal mesotheliomas in F344 rats given intragastric N-propyl-N-nitrosourea and histochemical, immunohistochemical, and ultrastructural characteristics of induced mesotheliomas."
|3.||Thymoma (Thymic Carcinoma)
|4.||Myeloid Leukemia (Leukemia, Myelocytic)
|5.||Body Weight (Weight, Body)
02/01/1976 - "Three groups of female Donryu rats were given a single gastric intubation of 800, 400, or 200 mg/kg body weight of 1-propyl-1-nitrosourea and one group of female Donryu rats was given a single subcutaneous injection of 1-propyl-1-nitrosourea. "
08/01/1987 - "Ovarian tumors were also rare in these strains of rats when given high doses of N-alkyl-N-nitrosoureas continuously in the drinking water for their life-span; however, relatively high incidences of Sertoli cell tumors or Sertoli cell tumors mixed with granulosa cell tumors were induced in Donryu rats after administration of either a 400 ppm N-ethyl-N-nitrosourea solution in the drinking water for 4 weeks or as a single dose of 200 mg N-propyl-N-nitrosourea per kg body weight by stomach tube. "