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papulacandin B
from Papularia sphaerosperma; inhibits growth of Candida albicans
Also Known As:
alpha-D-Glucopyranose, 1,16-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-(8-hydroxy-1-oxo-2,4,6-decatrienyl)-beta-D-galactopyranosyl)-, 3-(7-hydroxy-8,14-dimethyl-2,4,8,10-hexadecatetraenoate)
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Glycosides: 2119
Aminoglycosides: 5131
papulacandin B: 2
Related Diseases
1.
Hypersensitivity (Allergy)
12/01/1997 - "
Addition of Ca2+ suppresses hypersensitivity to papulacandin B and septation and branching phenotypes.
"
12/01/1997 - "
cps1+, a Schizosaccharomyces pombe gene homolog of Saccharomyces cerevisiae FKS genes whose mutation confers hypersensitivity to cyclosporin A and papulacandin B.
"
12/01/1997 - "
We have found that the cps1-12 mutation also confers (i) hypersensitivity to the immunosuppressant cyclosporin A (CsA), (ii) hypersensitivity to the drug papulacandin B, which specifically inhibits 1,3-beta-D-glucan synthesis both in vivo and in vitro, and (iii) thermosensitive growth at 37 degrees C.
"
2.
Type 1 Spherocytosis
11/01/1990 - "
The morphological sph1 mutant is resistant to papulacandin B, and its cell wall contains less glycoprotein II (but not less glycoprotein I) than the parental wild-type strain, although glycoprotein II is still synthesized and released into the growth medium.
"
Related Drugs and Biologics
1.
Cyclosporine (Ciclosporin)
2.
Immunosuppressive Agents (Immunosuppressants)
3.
Glycoproteins (Glycoprotein)
4.
Cytisus-type anti-H(O) lectins (CSA-I)