zomepirac (Zomax)

10/01/1984 - "Pain relief in this double-blind crossover study was significantly greater after zomepirac than after placebo. "
01/01/1980 - "Efficacy of zomepirac in oral surgical pain."
01/01/1983 - "An open, multi-centre study was carried out in patients with various moderate to severe painful conditions to assess the effectiveness of zomepirac in relieving pain. "
10/01/1984 - "Pain elicited by selective activation of nociceptive fibers was inhibited by the administration of a single oral dose of 100 mg zomepirac. "
10/01/1984 - "Central effects of zomepirac on pain evoked by intraneural stimulation in man."

07/01/1983 - "Plasma levels of zomepirac at termination of anaesthesia were consistent with the differences in remedication profiles and showed significant correlations with initial postoperative pain intensity, as assessed by an ordinal descriptive scale (r = 0.431, p = 0.025) and time to remedication (r = 0.541, p = 0.004), thus adding validity to the model."
07/01/1983 - "Three regimens of oral zomepirac premedication - 100 mg and 200 mg administered one hour preoperatively, and 100 mg administered 30 minutes preoperatively - were compared in terms of the control of postoperative pain. "
09/01/1981 - "The efficacy of zomepirac has been demonstrated primarily in acute forms of pain with associated inflammatory processes including postdental-extraction, postpartum, and postoperative pain. "
09/01/1986 - "A double-blind study comparing single dose of intramuscularly injected zomepirac to meperidine in the treatment of postoperative pain."
04/01/1985 - "Zomepirac, dihydrocodeine and placebo compared in postoperative pain after day-case surgery. "

04/01/1982 - "Preliminary studies suggest that zomepirac may also be effective in patients with chronic cancer pain who have not been previously maintained on strong analgesics, but further experience is needed to clarify its usefulness in this difficult treatment area."
01/01/1980 - "Double-blind comparisons of zomepirac and oxycodone with APC in cancer pain."
11/01/1981 - "Zomepirac sodium, 100 mg, appears to be an acceptable alternative to narcotic combinations such as oxycodone with APC in the management of moderate to severe cancer pain. "
05/15/1984 - "Patients with chronic cancer pain have greater positive mood effects after the narcotic, morphine, than after the non-steroidal antiinflammatory analgesic, zomepirac, and this appears to be independent of analgesic activity. "

06/01/1982 - "This acute renal failure improved upon cessation of zomepirac treatment. "
01/05/2018 - "Neutrophil depletion protects against zomepirac-induced acute kidney injury in mice."
01/01/1983 - "Zomepirac-related acute renal failure."
12/01/1981 - "Acute renal failure and zomepirac."
06/01/1982 - "We report here a case of nonoliguric acute renal failure associated with zomepirac sodium therapy. "

11/01/1981 - "Analgesic efficacy of zomepirac sodium in patients with pain due to cancer."
01/01/1980 - "A twin crossover assay of oral zomepirac and intramuscular morphine was completed in 159 cancer patients with postoperative pain. "
01/01/1980 - "Relative analgesic potency of oral zomepirac and intramuscular morphine in cancer patients with postoperative pain."
11/01/1981 - "In a single-dose, a double-blind crossover study in 40 patients with chronic pain due to advanced cancer, zomepirac sodium (Zomax), a new, single-entity, non-narcotic analgesic, was compared to oxycodone with APC (Percodan) and placebo. "