estrone sulfotransferase

Also Known As:

SULT1E1 protein, human; Ste protein, rat; Sult1e1 protein, mouse; estrogen sulfotransferase; sulfotransferase SULT1E1; sulfotransferase family 1E, estrogen-preferring, member 1 protein, human; sulfotransferase family 1E, member 1 protein, mouse; sulfotransferase, estrogen preferring protein, rat

Networked: 79 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Sulfur Group Transferases
      - Sulfotransferases: 442
        estrone sulfotransferase: 79

Experts

1.	Sasano, Hironobu: 11 articles (01/2021 - 01/2002)
2.	Suzuki, Takashi: 10 articles (07/2011 - 01/2002)
3.	Miki, Yasuhiro: 6 articles (07/2011 - 06/2003)
4.	Xie, Wen: 5 articles (01/2020 - 06/2012)
5.	Xu, Meishu: 5 articles (01/2020 - 06/2012)
6.	Nakata, Taisuke: 5 articles (02/2009 - 06/2003)
7.	Moriya, Takuya: 5 articles (06/2006 - 01/2002)
8.	Ishida, Takanori: 4 articles (10/2010 - 01/2002)
9.	Ebina, Keiichi: 3 articles (01/2022 - 10/2020)
10.	Sakurai, Eiko: 3 articles (01/2022 - 10/2020)

Related Diseases

1.	Endometriosis 12/01/2007 - "To elucidate the intracrinology of endometriotic tissues, the authors analyze the expression of aromatase and E2-inactivating estrogen sulfotransferase (EST) in paired biopsies obtained simultaneously from the endometrium and from endometrial lesions of each of 35 patients with peritoneal or ovarian endometriosis and in cycling endometria from 33 women without endometriosis. " 12/01/2007 - "Expression of aromatase and estrogen sulfotransferase in eutopic and ectopic endometrium: evidence for unbalanced estradiol production in endometriosis." 04/01/2016 - "Effects of steroid hormone on estrogen sulfotransferase and on steroid sulfatase expression in endometriosis tissue and stromal cells." 01/01/2022 - "The main enzymatic pathways involved in the intracrinology of endometriosis such as aromatase (CYP19A1), 17β-hydroxysteroid dehydrogenase (HSD17B) type 1, type 2 and type 5, steroid sulfatase (STS), estrogen sulfotransferase (SULT1E1) were assessed with a critical perspective on their role in disease endocrine phenotyping, drug resistance and as therapeutic targets. " 12/01/2007 - "In this study, we have looked at the mRNA expression and protein levels of a range of steroidogenic enzymes [aromatase, 17beta-hydroxysteroid dehydrogenases (17beta-HSD) type 1, 2 and 4, estrogen sulfotransferase (EST) and steroid sulfatase (STS)] in eutopic and ectopic endometrium of patients (n = 14) with deep-infiltrative endometriosis as well as in disease-free endometrium (n = 48) using real-time PCR and immunocytochemistry. "
2.	Acute Kidney Injury (Acute Renal Failure) 01/01/2020 - "Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice."
3.	Breast Neoplasms (Breast Cancer) 03/01/1992 - "In another series of recent studies the presence of very strong estrogen sulfotransferase activity has been shown in one breast cancer cell line, the MDA-MB-468. " 01/01/2020 - "Breast cancer pathogenesis is linked to the intra-tumoral estrogen sulfotransferase (hSULT1E1) expressions regulated by cellular redox dependent Nrf-2/NFκβ interplay." 01/01/2019 - "Estrogen Sulfotransferase Induction Inhibits Breast Cancer Cell Line MCF-7 Proliferation." 01/01/2011 - "In the breast cancer tissue, 17β-estradiol (E(2)) is inactivated by sulfation and the expression level of estrogen sulfotransferase (SULT1E1) is inversely correlated with its malignancy. " 03/20/2009 - "Expression of Estrogen Sulfotransferase 1E1 and Steroid Sulfatase in Breast Cancer: A Immunohistochemical Study."
4.	Endometrial Neoplasms (Endometrial Cancer) 11/01/1984 - "Characterization of cytosolic estrogen sulfotransferase from RL95-2 endometrial cancer cells." 09/01/2004 - "We first examined the expression of steroid sulfatase and estrogen sulfotransferase in 6 normal endometrium and 76 endometrial carcinoma using immunohistochemistry to elucidate the possible involvement of steroid sulfatase and estrogen sulfotransferase. " 09/01/2004 - "However, the status of steroid sulfatase and/or estrogen sulfotransferase in human endometrial carcinoma has not been examined. " 09/01/2004 - "Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma." 01/01/2007 - "Levels and activity of the enzyme estrogen sulfotransferase (EST) have been reported to play an important role in the regulation of in situ estrogen levels in human breast, prostate, and endometrial cancer. "
5.	Carcinoma (Carcinomatosis) 07/04/2011 - "Steroid sulfatase and estrogen sulfotransferase in human carcinomas." 10/01/1983 - "Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma." 02/01/2009 - "Steroid sulfatase and estrogen sulfotransferase in colon carcinoma: regulators of intratumoral estrogen concentrations and potent prognostic factors." 09/01/2004 - "Results of our study demonstrated that increased steroid sulfatase and decreased estrogen sulfotransferase expression in human endometrial carcinomas may result in increased availability of biologically active estrogens and may be related to estrogen-dependent biological features of carcinoma." 01/01/2021 - "Moreover, not only ERs but also estrogen-related enzymes, such as aromatase, steroid sulfatase (STS), and estrogen sulfotransferase (EST), have been reported in the biological/clinical behavior of various hormone-dependent carcinomas but not studied in urinary bladder carcinoma. "

Related Drugs and Biologics

1.	Steryl-Sulfatase (Steroid Sulfatase)
2.	Aromatase (CYP19)
3.	Enzymes
4.	Proteins (Proteins, Gene)
5.	Messenger RNA (mRNA)
6.	Oxidoreductases (Dehydrogenase)
7.	Estrogens (Estrogen)
8.	Estrone
9.	3 (or 17)-beta-hydroxysteroid dehydrogenase
10.	estrone sulfatase