|1.||Pasqualini, Jorge R: 4 articles (10/2007 - 02/2003)|
|2.||Pasqualini, J R: 4 articles (05/2007 - 01/2001)|
|3.||Argenta, Peter A: 2 articles (03/2009 - 01/2009)|
|4.||Blomquist, Charles H: 2 articles (03/2009 - 01/2009)|
|5.||Ryu, Hyung S: 2 articles (03/2009 - 01/2009)|
|6.||Chura, Justin C: 2 articles (03/2009 - 01/2009)|
|7.||Chetrite, G S: 2 articles (05/2007 - 01/2001)|
|8.||Liebl, Renate: 2 articles (12/2004 - 12/2002)|
|9.||von Angerer, Erwin: 2 articles (12/2004 - 12/2002)|
|10.||Osawa, Yoshio: 2 articles (07/2003 - 06/2003)|
|1.||Breast Neoplasms (Breast Cancer)
10/01/1991 - "These studies could form the basis for the design of a potent estrone sulfatase inhibitor which would have potential therapeutic activity in the management of breast cancer."
01/01/2003 - "Our in vitro studies indicate that the oxathiazine compounds have inhibitory activity on estrone sulfatase in MCF-7 human breast cancer cells. "
12/01/2004 - "Stilbene-based inhibitors of estrone sulfatase with a dual mode of action in human breast cancer cells."
08/12/1999 - "OMATE potently inhibited estrone sulfatase (E1-STS) activity and was similar to EMATE (>99% inhibition at 0.1 microM in MCF-7 breast cancer cells). "
01/18/1999 - "We report the development of (E)- and (Z)-4-hydroxytamoxifen sulfamates as estrone sulfatase inhibitors, potential therapeutic agents for the treatment of breast cancer. "
|2.||Leiomyoma (Uterine Fibroids)
09/01/1990 - "Estrone sulfatase activity in the uterine leiomyoma was 0.49 +/- 0.08 nmol/h/mg protein (Mean +/- SE), and was lower than that in the myometrial tissue (0.76 +/- 0.09). "
06/01/1990 - "Estrone sulfatase activity in human uterine leiomyoma."
06/01/1990 - "In this study, estrone sulfatase (E1SF) activity and concentrations of estrone (E1) and estrone sulfate (E1S) were measured in endometrial, leiomyoma, and myometrial tissues of the same human uterus (n = 11) with a leiomyoma. "
09/01/1990 - "These results suggest that estrone sulfate is hydrolyzed mainly by estrone sulfatase in the endometrium and myometrium surrounding leiomyoma nodes and the estrone formed may affect the growth of leiomyoma."
09/01/1990 - "In this study, we investigated both the estrone formation (estrone sulfatase activity) and the transformation from estrone to estrone sulfate (estrone sulfotransferase activity) in human leiomyoma tissue. "
01/01/1997 - "Estrone sulfatase activity measured simultaneously in the cytosol fractions of some specimens was much higher in cancer tissues than in noncancerous tissues (0.02 < p < 0.05). "
01/01/1999 - "Furthermore, our data support the concept that nonsteroidal estrone sulfatase inhibitors may be useful as therapeutic agents for estrogen-dependent breast cancers."
07/01/1998 - "Further, our data support the concept that estrone sulfatase inhibitors may be useful as therapeutic agents for estrogen-dependent breast cancers."
07/01/1998 - "Thus, inhibitors of estrone sulfatase have potential for the treatment of estrogen-dependent breast cancers. "
09/01/1996 - "Further, our data support the concept that estrone sulfatase inhibitors may be useful as therapeutic agents for estrogen-dependent breast cancers."
10/01/1991 - "The human placental microsome and breast carcinoma mitochondrial/microsomal estrone sulfatase activity were characterized and inhibition studies performed. "
10/01/1991 - "Inhibition of estrone sulfatase enzyme in human placenta and human breast carcinoma."
12/01/2002 - "All of the new sulfamates were studied for their inhibitory effects on the enzyme estrone sulfatase from human breast cancer cells and their (anti)hormonal activities in stably transfected human MCF-7/2a mammary carcinoma cells. "
12/01/1991 - "Our results suggest that synthetic progestogens can influence the estrone sulfatase activity measured in human breast carcinoma tissues. "
12/01/1991 - "In vitro effect of synthetic progestogens on estrone sulfatase activity in human breast carcinoma."
|5.||Breast Ductal Carcinoma
01/01/1985 - "Two estrogen sulfatases, arylsulfatase C-estrone sulfatase (ASC-ES) and d-equilenin sulfatase (EqS) were demonstrated histochemically in the normal human female breast, in benign breast diseases and in infiltrating mammary ductal carcinomas to study their significance in the pathogenesis of epithelial proliferations. "
|2.||estrone sulfate (Evex)
|6.||3 (or 17)-beta-hydroxysteroid dehydrogenase