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dolichol kinase

CTP is phosphate donor

Also Known As:

dolichol phosphokinase

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        dolichol kinase: 7

Experts

1.	Claris, Olivier: 1 article (01/2021)
2.	Collardeau-Frachon, Sophie: 1 article (01/2021)
3.	Echeverry, Fabio A: 1 article (01/2021)
4.	Fischer, Judith: 1 article (01/2021)
5.	Granato, Michael: 1 article (01/2021)
6.	Hausser, Ingrid: 1 article (01/2021)
7.	Hsu, Jerry: 1 article (01/2021)
8.	Jain, Roshan A: 1 article (01/2021)
9.	Jonca, Nathalie: 1 article (01/2021)
10.	Komlosi, Katalin: 1 article (01/2021)

Related Diseases

1.	Inflammation (Inflammations) 09/01/1983 - "The endogenous level of dolichol phosphate and dolichol kinase activity were increased in microsomes 24 h after inflammation. " 09/01/1983 - "The increase of dolichol phosphate in inflammation is most likely due to both greater availability of dolichol and an increase in the level of CTP-dependent dolichol kinase. " 05/10/1981 - "Effects of turpentine-induced inflammation on the synthesis of dolichol-linked intermediates of N-glycosylation and the phosphorylation of dolichol by CTP-dependent dolichol kinase."
2.	Vision Disorders (Hemeralopia) 01/01/2021 - "DOLK-CDG is such a rare subtype, resulting from a defect in dolichol kinase, in which the congenital skin phenotype (often ichthyosis) is later associated with variable extracutaneous features such as dilatative cardiomyopathy, epilepsy, microcephaly, visual impairment, and hypoglycemia and may lead to a fatal course. "
3.	Nervous System Diseases (Neurological Disorders) 01/01/2021 - "We uncovered mutations in eight genes critical for startle behavior, including two genes encoding proteins associated with human neurological disorders, Dolichol kinase (Dolk), a broadly expressed regulator of the glycoprotein biosynthesis pathway, and the potassium Shaker-like channel subunit Kv1.1. We demonstrate that Kv1.1 and Dolk play critical roles in the spinal cord to regulate movement magnitude during the startle response and spontaneous swim movements. "
4.	Neoplasms (Cancer) 06/15/1988 - "The dolichol monophosphatase activities in microsomal fractions from hepatomas and controls did not show any major differences, whereas the activity of the CTP-dependent dolichol kinase was increased in tumor microsomes. "
5.	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 12/01/2013 - "Severe, fatal multisystem manifestations in a patient with dolichol kinase-congenital disorder of glycosylation."

Related Drugs and Biologics

1.	Dolichols
2.	Cytidine Triphosphate (CTP)
3.	Turpentine
4.	Proteins (Proteins, Gene)
5.	Potassium
6.	Phosphates (Orthophosphate)
7.	Glycoproteins (Glycoprotein)
8.	Cytidine
9.	dolichol monophosphate (dolichyl phosphate)
10.	dolichyl-phosphatase