dihydroxyacid dehydratase

catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids

Also Known As:

2,3-dihydroxyisovalerate dehydratase; Dihydroxyacid dehydratase, S cerevisiae; ILV3 protein, S cerevisiae; YJR016C protein, S cerevisiae; alpha,beta-dihydroxyisovalerate dehydratase; dihydroxy-acid dehydratase, E coli; ilvD protein, E coli

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - Carbon-Oxygen Lyases
      - Hydro-Lyases: 266
        dihydroxyacid dehydratase: 3

Experts

1.	Anokhina, Galina B: 1 article (10/2021)
2.	Eprintsev, Alexander T: 1 article (10/2021)
3.	Fedorin, Dmitry N: 1 article (10/2021)
4.	Igamberdiev, Abir U: 1 article (10/2021)

Related Diseases

1.	Poisoning 12/14/1978 - "Dihydroxyacid dehydratase: the site of hyperbaric oxygen poisoning in branch-chain amino acid biosynthesis." 01/01/1984 - "coli by paraquat and hyperbaric oxygen were shown to be prevented by inclusion in the medium of a nearly identical profile of specific amino acids, including branched-chain amino acids, which were required because of poisoning of their biosynthesis at the dihydroxyacid dehydratase site, and stringency has been induced by hyperbaric oxygen poisoning. "
2.	Hypoxia (Hypoxemia) 10/01/2021 - "We conclude that the expression of two genes encoding dihydroxyacid dehydratase reveals the opposite or different patterns of regulation by light, anoxia and salinity. " 10/01/2021 - "Effects of light, anoxia and salinity on the expression of dihydroxyacid dehydratase in maize."

Related Drugs and Biologics

1.	Oxygen (Dioxygen)
2.	Amino Acids
3.	Paraquat
4.	Branched-Chain Amino Acids