coumarin 7-hydroxylase

CYP2A5 hyrdoxylates DHEA in at least three positions (7alpha, 7beta, and 2alpha); some enzyme preparations hydroxylate at position 3 & position 7; if cytochrome P-450coh is mutated at position 209, its substrate specificity is changed from coumarin hydroxylation (coh) to steroid hydroxylation
Also Known As:
CYP2A6 protein, human; Cyp2a3 protein, rat; Cyp2a5 protein, mouse; coumarin hydroxylase; cytochrome P-450coh; cytochrome P450 2A5, mouse; cytochrome P450, family 2, subfamily A, polypeptide 3a, rat; cytochrome P450, family 2, subfamily A, polypeptide 6, human; cytochrome P450, family 2, subfamily a, polypeptide 5, mouse
Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results


1. Kulikova, L N: 1 article (05/2004)

Related Diseases

1. Necrosis
2. Lung Injury
3. Neoplasms (Cancer)
4. Infection
5. Hepatocellular Carcinoma (Hepatoma)

Related Drugs and Biologics

1. pyrazole
2. Cytochrome P-450 CYP2B1 (PROD)
3. Transforming Growth Factor alpha (TGF-alpha)
4. Transforming Growth Factors (Transforming Growth Factor)
5. Testosterone (Sustanon)
6. Cytochrome P-450 Enzyme System (Cytochrome P450)
7. Cocaine (Cocaine HCl)
8. Butylated Hydroxytoluene (BHT)
9. coumarin 7
10. 7-hydroxycoumarin (umbelliferone)