HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

CDP reductase

includes deoxy analog

Also Known As:

Cytidine diphosphate reductase; deoxycytidine diphosphate reductase

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Ribonucleotide Reductases: 865
      - Ribonucleoside Diphosphate Reductase: 26
        CDP reductase: 8

Related Diseases

1.	Neoplasms (Cancer) 02/10/1982 - "The decrease in CDP reductase activity which accompanied the decrease in Ehrlich tumor cell proliferation in vivo could be correlated with the decrease in the dye fraction component. " 02/10/1982 - "It was found that the addition of the effector-binding component (dye fraction) to cell-free extracts of Ehrlich tumor cells stimulated CDP reductase activity. " 06/01/1984 - "The activities of cytidine triphosphate synthetase and cytidine diphosphate reductase in the livers of YS-bearing rats were elevated compared with those in the livers of rat ascites hepatoma AH 7974- or Walker 256 carcinosarcoma-bearing rats and normal rats, while the activities of dCyd kinase, 5'-nucleotidase (EC 3.1.3.5), and dCyd deaminase were similar between normal rat livers and tumor-bearing rat livers. "
2.	Hepatocellular Carcinoma (Hepatoma) 01/01/1985 - "The postulation that the activity of key enzymes that reveal marked increases should be potential targets for anticancer chemotherapy (47) was supported by new evidence on the alterations of CDP reductase, CTP synthetase and OMP decarboxylase in hepatoma 3924A cell cultures. " 06/01/1984 - "The activities of pyrimidine de novo synthesis enzymes, such as cytidine triphosphate synthetase (EC 6.3.4.2) and cytidine diphosphate reductase (EC 1.17.4.1), in YS were higher than those in both rat ascites hepatoma AH 7974 and Walker 256 carcinosarcoma, the transplantations of which did not induce increased excretion of dCyd into urine of the hosts. " 06/01/1984 - "The activities of cytidine triphosphate synthetase and cytidine diphosphate reductase in the livers of YS-bearing rats were elevated compared with those in the livers of rat ascites hepatoma AH 7974- or Walker 256 carcinosarcoma-bearing rats and normal rats, while the activities of dCyd kinase, 5'-nucleotidase (EC 3.1.3.5), and dCyd deaminase were similar between normal rat livers and tumor-bearing rat livers. "
3.	Ascites 01/13/1984 - "CDP reductase was separated from the cytosol of rat Yoshida ascites sarcoma. " 01/13/1984 - "Separation of cytidine diphosphate reductase from rat Yoshida ascites sarcoma." 06/01/1984 - "The activities of pyrimidine de novo synthesis enzymes, such as cytidine triphosphate synthetase (EC 6.3.4.2) and cytidine diphosphate reductase (EC 1.17.4.1), in YS were higher than those in both rat ascites hepatoma AH 7974 and Walker 256 carcinosarcoma, the transplantations of which did not induce increased excretion of dCyd into urine of the hosts. " 06/01/1984 - "The activities of cytidine triphosphate synthetase and cytidine diphosphate reductase in the livers of YS-bearing rats were elevated compared with those in the livers of rat ascites hepatoma AH 7974- or Walker 256 carcinosarcoma-bearing rats and normal rats, while the activities of dCyd kinase, 5'-nucleotidase (EC 3.1.3.5), and dCyd deaminase were similar between normal rat livers and tumor-bearing rat livers. "
4.	Sarcoma (Soft Tissue Sarcoma) 01/13/1984 - "CDP reductase was separated from the cytosol of rat Yoshida ascites sarcoma. " 01/13/1984 - "Separation of cytidine diphosphate reductase from rat Yoshida ascites sarcoma."
5.	Experimental Liver Neoplasms 10/01/1964 - "VI. THE CYTIDINE DIPHOSPHATE REDUCTASE SYSTEM FROM NOVIKOFF HEPATOMA."

Related Drugs and Biologics

1.	Enzymes
2.	CTP synthetase
3.	5'-Nucleotidase (5' Nucleotidase)
4.	Thymidine Kinase
5.	Phosphotransferases (Kinase)
6.	Orotidine-5'-Phosphate Decarboxylase (Orotidine 5 Phosphate Decarboxylase)
7.	Coloring Agents (Dyes)
8.	DCMP Deaminase (Deoxycytidylate Deaminase)
9.	Antineoplastic Agents (Antineoplastics)
10.	pyrimidine

Related Therapies and Procedures

1.	Transplantation
2.	Drug Therapy (Chemotherapy)