adenylylsulfate reductase

Also Known As:

5'-adenylylsulfate reductase; AMP sulfite-(acceptor) oxidoreductase; APR1 protein, Arabidopsis; APS reductase; AdoPSO4 reductase; adenosine 5'phosphosulfate reductase; adenylyl phosphosulfate reductase

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Oxidoreductases Acting on Sulfur Group Donors: 5
      - adenylylsulfate reductase: 7

Experts

1.	Carroll, Kate S: 3 articles (09/2013 - 11/2008)
2.	Hong, Jiyoung A: 2 articles (09/2009 - 11/2008)
3.	Anoman, Armand D: 1 article (01/2019)
4.	Benstein, Ruben M: 1 article (01/2019)
5.	Blau, Samira: 1 article (01/2019)
6.	Bräutigam, Andrea: 1 article (01/2019)
7.	Fernie, Alisdair R: 1 article (01/2019)
8.	Flores-Tornero, María: 1 article (01/2019)
9.	Kopriva, Stanislav: 1 article (01/2019)
10.	Krueger, Stephan: 1 article (01/2019)

Related Diseases

1.	Tuberculosis (Tuberculoses) 09/10/2009 - "tuberculosis APS reductase that is in accord with the results presented here as well as prior structural data reported for Pseudomonas aeruginosa APS reductase and related enzymes. " 09/06/2002 - "tuberculosis proceeds from sulfate through APS, which is acted on by APS reductase in the first committed step toward cysteine and methionine. " 09/01/2013 - "Mycobacterium tuberculosis (Mtb) adenosine 5'-phosphosulfate (APS) reductase (APR) catalyzes the first committed step in sulfate reduction for the biosynthesis of essential reduced sulfur-containing biomolecules, such as cysteine, and is essential for survival in the latent phase of tuberculosis (TB) infection. "
2.	Starvation 01/01/2019 - "Key genes in the sulfate starvation response, such as the adenosine 5'phosphosulfate reductase genes, along with sulfate transporters, especially those involved in sulfate translocation in the plant, were induced in the PPSB-deficient lines. " 07/01/2004 - "In the leaves, the sulfate transporters, ATP-sulfurylase and APS-reductase were induced by S-starvation with the most mature leaf showing increased mRNA abundance first. " 07/01/2004 - "As the increase in root proliferation was not as great as the increase in mRNA pools, it was clear that there was a higher cellular abundance of the mRNAs for sulfate transporters, ATP-sulfurylase, and APS-reductase in response to sulfur starvation. " 07/01/2004 - "Similarly a group 2, probable low affinity-type sulfate transporter, ZmST2;1, and also ATP-sulfurylase and APS-reductase but not OAS(thiol)lyase were induced by S-starvation and showed highest expression in the upper section of the root. " 01/01/2008 - "Sulfur and phosphorus deprivation increased this expression level, while nitrogen starvation repressed APS reductase mRNA transcript and protein levels. "
3.	Latent Tuberculosis 11/13/2008 - "APS reductase catalyzes the first committed step in bacterial sulfate reduction and is a validated drug target against latent tuberculosis infection. "
4.	Infections 09/01/2013 - "Mycobacterium tuberculosis (Mtb) adenosine 5'-phosphosulfate (APS) reductase (APR) catalyzes the first committed step in sulfate reduction for the biosynthesis of essential reduced sulfur-containing biomolecules, such as cysteine, and is essential for survival in the latent phase of tuberculosis (TB) infection. "
5.	Latent Infection 09/10/2009 - "Mycobacterium tuberculosis adenosine-5'-phosphosulfate (APS) reductase is an iron-sulfur protein and a validated target to develop new antitubercular agents, particularly for the treatment of latent infection. "

Related Drugs and Biologics

1.	Sulfates (Sulfates, Inorganic)
2.	Sulfur
3.	Messenger RNA (mRNA)
4.	Cysteine (L-Cysteine)
5.	Sulfate Transporters
6.	Sulfhydryl Compounds (Thiols)
7.	Sulfate Adenylyltransferase (ATP Sulfurylase)
8.	Proteins (Proteins, Gene)
9.	Phosphorus (Red Phosphorus)
10.	Nitrogen