vasicine

RN given refers to (R)-isomer

Also Known As:

peganine; peganine hydrochloride dihydrate; vasicine hydrochloride, (R)-isomer; vasicine monohydrochloride, (R)-isomer; vasicine, (+-)-isomer; (R)-1,2,3,9-tetrahydropyrrolo(2,1-b)quinazolin- 3-ol

Networked: 20 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - vasicine: 20
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - vasicine: 20

Experts

1.	Cheng, Xuemei: 2 articles (10/2018 - 01/2015)
2.	Liu, Wei: 2 articles (10/2018 - 01/2015)
3.	Wang, Changhong: 2 articles (10/2018 - 01/2015)
4.	Wang, Yongli: 2 articles (10/2018 - 01/2015)
5.	Khaliq, Tanvir: 2 articles (10/2013 - 11/2008)
6.	Ilango, Kaliappan: 1 article (02/2021)
7.	Nandhini, Sundaresan: 1 article (02/2021)
8.	Hari Ty, Sri: 1 article (01/2021)
9.	Pasala, Praveen Kumar: 1 article (01/2021)
10.	Sudha Ty, Sree: 1 article (01/2021)

Related Diseases

1.	Cognitive Dysfunction 01/01/2023 - "Therefore, it is of interest to evaluate the in-vivo efficacy of vasicine for treating neuroinflammation-induced cognitive impairments in the zebrafish model. " 01/01/2023 - "Attenuation of cognitive dysfunction in all three neuroinflammation zebrafish models by vasicine in this study may recommend vasicine as a potential molecule for treating neuroinflammatory and neurodegenerative diseases."
2.	Neuroinflammatory Diseases 01/01/2023 - "Therefore, it is of interest to evaluate the in-vivo efficacy of vasicine for treating neuroinflammation-induced cognitive impairments in the zebrafish model. " 01/01/2023 - "Attenuation of cognitive dysfunction in all three neuroinflammation zebrafish models by vasicine in this study may recommend vasicine as a potential molecule for treating neuroinflammatory and neurodegenerative diseases."
3.	Stomach Ulcer (Gastric Ulcer) 10/15/2013 - "Anti-secretory and cyto-protective effects of peganine hydrochloride isolated from the seeds of Peganum harmala on gastric ulcers." 10/15/2013 - "Peganine hydrochloride was evaluated against cold restraint (CRU), aspirin (AS), alcohol (AL) and pyloric ligation (PL) induced gastric ulcer models in rats. "
4.	Cough 11/01/2018 - "Current study directed the standardization of eminent biomarker Vasicine in a natural cough syrup. " 01/01/2014 - "Methods are validated according to ICH guidelines and can be adopted for the routine analysis of vasicine, glycyrrhizin, eugenol and cineole in herbal cough syrup. " 01/01/2014 - "A new simple, rapid, selective and precise high performance thin layer chromatographic (HPTLC) method has been developed for simultaneous estimation of vasicine, glycyrrhizin, eugenol, and cineole in herbal cough syrup. " 12/01/2015 - "We investigated the antitussive effects of a KJ (30 ml/day; 762 mg genuine extracts with standardized contents of 0.2 mg/ml vasicine, 0.8 mg/ml chicoric acid, and 0.03 mg/ml eleutherosides B and E), bromhexine hydrochloride (24 mg/30 ml/day) and PL on cough and blood markers. "
5.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2023 - "Attenuation of cognitive dysfunction in all three neuroinflammation zebrafish models by vasicine in this study may recommend vasicine as a potential molecule for treating neuroinflammatory and neurodegenerative diseases."

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	Alkaloids
3.	Cholinesterase Inhibitors (Anticholinesterases)
4.	Therapeutic Uses
5.	Glycyrrhizic Acid (Glycyrrhizin)
6.	Ligands
7.	Harmine (Telepathine)
8.	Eugenol
9.	Bronchodilator Agents (Bronchodilators)
10.	Bromhexine (Bisolvon)

Related Therapies and Procedures

1.	Ligation