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3,5,3',5'-tetrafluorodiethylstilbestrol
structure
Also Known As:
3,3',5,5'-TF-DES; TF-DES
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzylidene Compounds: 10
Stilbenes: 657
Stilbestrols: 1
Diethylstilbestrol: 1652
3,5,3',5'-tetrafluorodiethylstilbestrol: 1
Related Diseases
1.
Neoplasms (Cancer)
06/01/1983 - "
These data established the ability of TF-DES not only to induce tumors but also to promote estrogen-dependent tumor growth after the initiation process.
"
06/01/1983 - "
The tumor induction frequency of TF-DES was the same as that of diethylstilbestrol, although the induction period was longer (approximately 9 months) than that of diethylstilbestrol (approximately 6 months).
"
2.
Carcinoma (Carcinomatosis)
06/01/1983 - "
TF-DES was estrogenic and was found to support in vivo growth of estrogen-dependent H-301 cells, a cell line derived from the primary estrogen-induced and -dependent renal clear-cell carcinoma of male Syrian hamster.
"
06/01/1983 - "
E-3',3",5',5"-Tetrafluorodiethylstilbestrol (TF-DES), a structural analogue of diethylstilbestrol synthesized as a possible noncarcinogenic estrogen, was found to induce renal clear-cell carcinoma in Syrian hamster.
"
Related Drugs and Biologics
1.
Estrogens (Estrogen)
2.
Diethylstilbestrol (Stilbestrol)