|1.||Grozinger, C M: 1 article (09/2014)|
|2.||Hefetz, A: 1 article (09/2014)|
|3.||Amsalem, E: 1 article (09/2014)|
|4.||Teal, P: 1 article (09/2014)|
|5.||Brock, Barry: 1 article (09/2011)|
|6.||Ly, Van T: 1 article (09/2011)|
09/05/2011 - "Precocene I induced hepatocellular necrosis in a dose- and time-dependent manner. "
03/01/1984 - "dose of precocene I (300 mg/kg) resulted in extensive hepatic damage as evidenced by a marked increase of plasma glutamic pyruvic transaminase levels and histologic observation in liver sections of severe centrolobular necrosis. "
02/15/1987 - "Piperonyl butoxide pretreatment limited both the liver GSH depletion and the hepatic necrosis normally caused by precocene I. These results are consistent with the view that the hepatotoxicity of precocene I is due to reactive metabolites formed through cytochrome P-450 mediated metabolism of precocene I."
09/01/2014 - "Precocene-I also decreased aggressiveness and increased ester-sterility signal production; these changes were rank-dependent, and affected mainly the most reproductive and the least aggressive workers, respectively, and could not be remedied by JH replacement therapy. "
09/01/2014 - "Precocene-I inhibits juvenile hormone biosynthesis, ovarian activation, aggression and alters sterility signal production in bumble bee (Bombus terrestris) workers."
|3.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|4.||Alanine Transaminase (SGPT)