low density lipoprotein inhibitor

01/01/2018 - "Once thought to simply be caused by passive retention of LDL in the vasculature, atherosclerosis studies over the past 40-50 years have uncovered a much more complex mechanism. "
06/01/2004 - "Further studies are required to define the role of LDL(-) in atherogenesis more precisely and to clarify mechanisms involved in endothelial cell activation."
02/01/2001 - "Familial hypercholesterolaemia (FH) is a powerful clinical model in which to study the predictive role of LDL in atherogenesis. "
09/01/1991 - "This study suggests that the modulation of gap-junctional communication by the balance of HDL and LDL in plasma may influence atherogenesis."
04/01/2023 - "Our computations show that a giant accumulation of LDL in the intima layer of the outer wall of the left anterior descending artery, especially in low WSS regions, may lead to atherosclerosis. "

09/01/1999 - "In conclusion, hypercholesterolemia can be due to particle-related slow clearance of LDL in some patients. "
06/01/2015 - "[Association between food behavior and hypercholesterolemia-LDL in university students]."
03/01/2014 - "LDLR deficiency, hypercholesterolemia and elevated plasma LDL in NS are associated with upregulation of PCSK9 and IDOL. "
04/01/2013 - "Hypercholesterolemia was diagnosed in 120 (22.3%; 95% CI 18.6-26.7), decreased HDL in 22 (4.1%; 95% CI 2.7-6.2), high LDL in 79 (14.7%; 95% CI 11.8-18.3), and high TG in 96 (17.8%, 95% CI 14.7-21.9) subjects. "
09/01/1986 - "The results suggest that the accumulation of plasma LDL in the arterial wall following hypercholesterolemia may induce alterations in arterial GAG composition, presumably by affecting GAG synthesis by medial smooth muscle cells."

04/19/2021 - "The presence of aggregation-prone LDL in the circulation predicted future cardiovascular events in patients with atherosclerotic cardiovascular disease. "
08/01/2015 - "IMPROVE-IT and genetics reaffirm the causal role of LDL in Cardiovascular Disease."
09/01/2011 - "A relatively greater and positive correlation between greater levels of RLP-C and SAA-LDL in obese subjects with MetS, in comparison with those without MetS, may be linked to the development of MetS-related cardiovascular disease."
02/12/2005 - "[Role of LDL in cardiovascular diseases. "
10/01/2000 - "High levels of small, dense LDL in plasma are associated with increased risk for cardiovascular disease. "

06/01/2019 - "Association between Lp(a) and small dense LDL in menopausal women without metabolic syndrome."
01/01/2018 - "The present review deals with the main molecular mechanisms involved in the modification of LDL in diabetes and metabolic syndrome and briefly describe the atherogenic effects that these modified LDLs exert on the arterial wall. "
12/01/2010 - "These results seem to consolidate the probability of increased sd-LDL in hypertriglyceridemic metabolic syndrome subjects. "
12/01/2008 - "The current data warrant further investigation into the role of lifestyle and therapeutic interventions that inhibit tissue-associated oxidation of LDL in the prevention of the metabolic syndrome."
11/01/2011 - "Effect of three consecutive meals on the physicochemical properties of HDL and LDL in individuals with the metabolic syndrome and patients with type 2 diabetes."

01/01/2020 - "Breakfast skipping may have a modest impact on weight loss and may increase LDL in the short term. "
09/01/2015 - "Blood lipid changes in the study results showed that there was no significant difference in TC, TG, and LDL in both groups; however, there was a significant interaction between the composite weight-loss dietary supplement intake and HDL-C as well as an increase in the HDL-C of DG. "
09/01/2005 - "Weight loss associated with reduced intake of carbohydrate reduces the atherogenicity of LDL in premenopausal women."
02/01/1985 - "To determine the mechanisms regulating plasma LDL levels, we used 131I-VLDL and 125I-LDL to measure the fractional catabolic rates (FCR), production rates (PR), and rates of interconversion of apoprotein B (apo B) in VLDL, intermediate density lipoprotein, and LDL in six hypertriglyceridemic subjects pre- and post-weight reduction. "
01/01/2010 - "The current study was designed to test the efficacy of auricular acupressure on weight reduction and serum total cholesterol (TC), total triglycerides (TG), high density lipids (HDL) and low density lipids (LDL) in an eight-week, randomized controlled trial of three groups of 84 adolescents aged 18-20 with a body mass index (BMI) of 23 or higher. "