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5-deazaflavin

Also Known As:

Pyrimido(4,5-b)quinoline-2,4(1H,3H)-dione

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Flavins: 50
        5-deazaflavin: 2
  - 3-Ring Heterocyclic Compounds
    - Flavins: 50
      - 5-deazaflavin: 2
Enzymes and Coenzymes: 1
- Coenzymes: 558
  - Flavins: 50
    - 5-deazaflavin: 2
Biological Factors: 2472
- Biological Pigments: 1
  - Flavins: 50
    - 5-deazaflavin: 2

Experts

1.	Abe, Tohru: 1 article (01/2020)
2.	Chen, Xiuhao: 1 article (01/2020)
3.	Fujiwara, Mamoru: 1 article (01/2020)
4.	Hayashi, Mikayo: 1 article (01/2020)
5.	Inoue, Yusuke: 1 article (01/2020)
6.	Itoh, Kimiko: 1 article (01/2020)
7.	Kaboso, Shaban A: 1 article (01/2020)
8.	Kaneko, Kentaro: 1 article (01/2020)
9.	Kawano, Yoshikazu: 1 article (01/2020)
10.	Kawasaki, Masanori: 1 article (01/2020)

Related Diseases

1.	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/01/2020 - "Delamanid (DLM), a nitro-dihydroimidazooxazole derivative currently approved for pulmonary multidrug-resistant tuberculosis (TB) therapy, is a prodrug activated by mycobacterial 7,8-didemethyl-8-hydroxy 5-deazaflavin electron transfer coenzyme (F420)-dependent nitroreductase (Ddn). "
2.	Neoplasms (Cancer) 11/15/2013 - "Based on previous reports of certain 5-deazaflavin derivatives being capable of activating the tumour suppressor p53 in cancer cells through inhibition of the p53-specific ubiquitin E3 ligase HDM2, we have conducted an structure-activity relationship (SAR) analysis through systematic modification of the 5-deazaflavin template. "

Related Drugs and Biologics

1.	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
2.	Ubiquitin
3.	Prodrugs
4.	Nitroreductases
5.	Coenzymes (Enzyme Cofactors)
6.	OPC-67683

Related Therapies and Procedures

1.	Therapeutics