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asialo-human chorionic gonadotropin

Also Known As:

asialo-HCG; desialo HCG; desialylated HCG

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Choriocarcinoma 02/01/1995 - "Asialo-hCG purified from a patient with choriocarcinoma had very potent TSH-like activity (468 microU hTSH/mg). " 04/01/1985 - "The PNA binding fractions were extracted and purified from urine of 2 patients with choriocarcinoma, and were quantitatively found to be asialo-hCG. " 09/20/1984 - "However, asialo-hCG was found in 2 out of 6 cases of choriocarcinoma. " 04/01/1985 - "Therefore, PNA-Sepharose affinity chromatography is an effective tool for the detection of desialylated hCG and may be useful also for the diagnosis of choriocarcinoma."
2.	Trophoblastic Neoplasms (Trophoblastic Tumor) 02/01/1995 - "However, hCG produced by some trophoblastic tumors, particularly asialo-hCG, has potent thyrotropic activity sufficient to cause clinically overt hyperthyroidism when produced excessively."
3.	Thyrotoxicosis 02/01/1995 - "We conclude that thyrotoxicosis with hyperemesis may be caused by circulating asialo-hCG with higher thyrotropic bioactivity." 02/01/1995 - "Pathogenic role of asialo human chorionic gonadotropin in gestational thyrotoxicosis."
4.	Thyroid Neoplasms (Thyroid Cancer) 10/01/1995 - "The desialylated hCG variant also interacts directly with recombinant hTSH receptors transfected into human thyroid cancer cells. "
5.	Infertility (Sterility) 01/01/1983 - "Six patients with unexplained infertility were administered a partially desialylated hCG preparation (Desialo hCG). "

Related Drugs and Biologics

1.	asialo-human chorionic gonadotropin
2.	Sepharose (Agarose)