aflatrem

tremorgenic toxin isolated from Aspergillus flavus; structure

Also Known As:

4H-3,15a-Epoxy-1-benzoxepino(6',7':6,7)indeno(1,2-b)indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R-(3alpha,5balpha,7abeta,13balpha,13cbeta,15aalpha))-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - aflatrem: 2

Experts

1.	Calvo, Ana M: 1 article (01/2007)
2.	Cary, Jeffrey W: 1 article (01/2007)
3.	Duran, Rocio M: 1 article (01/2007)

Related Diseases

1.	Tremor (Tremors) 07/15/1986 - "The potent tremorgenic neurotoxins lolitrem B and aflatrem: a comparison of the tremor response in mice." 07/15/1986 - "Tremor dose-response curves were determined for mice dosed with the ryegrass neurotoxin lolitrem B, and the tremor-genic mycotoxin aflatrem. "
2.	Nervous System Diseases (Neurological Disorders) 01/01/2007 - "Aflatrem is a potent tremorgenic mycotoxin known to lead to neurological disorders. "

Related Drugs and Biologics

1.	Mycotoxins
2.	Neurotoxins
3.	lolitrem B

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