|1.||Mukherjee, Asama: 1 article (01/2009)|
|2.||Saxena, Ajit Kumar: 1 article (01/2009)|
|3.||Bhagat, Madhulika: 1 article (01/2009)|
|4.||Dutta, Sushanta: 1 article (01/2009)|
|5.||Sanyal, Utpal: 1 article (01/2009)|
|6.||Chashoo, Gousia: 1 article (01/2009)|
01/01/1994 - "Eleven patients with solid tumors for whom effective therapy was not available entered a phase I study of mitonafide given as a short intravenous (i.v.) infusion daily for 3 consecutive days. "
08/01/1992 - "Phase I study of mitonafide in solid tumors."
01/01/2009 - "Compared to Mitonafide and CCNU used as standards it also significantly inhibited DNA and RNA synthesis in EAC tumor cells in vitro at 8 microM concentration."
|2.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/01/1996 - "Phase II study of mitonafide in non-small cell lung cancer (NSCLC)."
08/01/1992 - "This phase I Mitonafide study in non-small cell lung cancer using a 120-hour continuous infusion (120 h. "
08/01/1992 - "Phase I study of mitonafide in 120 hour continuous infusion in non-small cell lung cancer."
01/01/1996 - "Forty-nine patients with previously untreated non-small cell lung cancer (NSCLC) and at least one measurable site received Mitonafide as a 120-hour continuous (5 days) infusion every 3 weeks. "
|3.||Colorectal Neoplasms (Colorectal Cancer)
01/01/1996 - "At the dose and schedule of administration used, Mitonafide is not active in colorectal cancer and induces severe myelotoxicity thus not deserving further studies in this indication."
01/01/1996 - "This study investigated the antitumoral activity in colorectal cancer and toxicity of a 5-day continuous infusion of a new cytostatic agent, Mitonafide, that had previously shown to be neurotoxic when administered as a short daily x 5 days infusion. "
01/01/1996 - "Phase II study of Mitonafide in advanced and relapsed colorectal cancer."
|4.||Chromosome Aberrations (Chromosome Abnormalities)
06/01/1983 - "At concentrations of 0.01 and 1.0 microM, respectively, mitonafide increased the frequency of sister chromatid exchanges and chromosome aberrations in CHO cells. "
06/01/1983 - "Mitonafide induced DNA strand breaks and chromosome abnormalities in cultured cells."
06/01/1983 - "Induction of DNA strand breaks and chromosome abnormalities by an imide derivative of 3-nitro-1,8-naphthalic acid (mitonafide) in Chinese hamster ovary cells."
|1.||DNA (Deoxyribonucleic Acid)
|2.||RNA (Ribonucleic Acid)
|4.||Aminocaproic Acids (EAC)