|1.||Albertioni, Freidoun: 3 articles (03/2006 - 11/2002)|
|2.||Fyrberg, Anna: 2 articles (01/2015 - 03/2006)|
|3.||Lotfi, Kourosh: 2 articles (01/2015 - 03/2006)|
|4.||Eriksson, Staffan: 2 articles (03/2006 - 03/2003)|
|5.||Albertioni, F: 2 articles (03/2002 - 04/2001)|
|6.||Eriksson, S: 2 articles (03/2002 - 04/2001)|
|7.||Ali, Ashraf: 1 article (03/2014)|
|8.||Lone, Khurram: 1 article (03/2014)|
|9.||Asery, Ali: 1 article (03/2014)|
|10.||He, Langping: 1 article (03/2014)|
11/01/1984 - "Studies were conducted to establish the relationship between deoxyguanosine kinase activity and human cytomegalovirus (HCMV) infection. "
07/01/2009 - "Novel deoxyguanosine kinase gene mutations and viral infection predispose apparently healthy children to fulminant liver failure."
11/01/1984 - "Deoxycytidine kinase activity which is associated with cytosolic deoxyguanosine kinase was unaffected by HCMV infection."
01/01/2012 - "Neonatal liver failure due to deoxyguanosine kinase deficiency."
02/01/2011 - "A group of 28 infants with severe progressive liver failure of unknown cause was recruited for post mortem search for deoxyguanosine kinase (DGUOK) gene mutations. "
03/01/2014 - "To determine the frequency of mitochondrial DNA depletion syndrome (MDS) in infants with cholestasis and liver failure and to further clarify the clinical, biochemical, radiologic, histopathologic, and molecular features associated with MDS due to deoxyguanosine kinase (DGUOK) and MPV17 gene mutations. "
02/01/2011 - "Post mortem identification of deoxyguanosine kinase (DGUOK) gene mutations combined with impaired glucose homeostasis and iron overload features in four infants with severe progressive liver failure."
02/01/2008 - "Published mutations in deoxyguanosine kinase (DGUOK) cause mitochondrial DNA depletion and a clinical phenotype that consists of neonatal liver failure, nystagmus and hypotonia. "
|3.||B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
03/14/2006 - "The pattern of deoxycytidine- and deoxyguanosine kinase activity in relation to messenger RNA expression in blood cells from untreated patients with B-cell chronic lymphocytic leukemia."
04/26/2001 - "The levels of thymidine kinase (TK), deoxycytidine kinase, deoxyguanosine kinase (dGK), and thymidylate kinase were determined in leukocyte extracts from patients with chronic lymphocytic leukemia (CLL) and acute myelocytic leukemia (AML). "
03/14/2006 - "Deoxycytidine kinase (dCK) and deoxyguanosine kinase (dGK) catalyze the first step in the intracellular cascade of fludarabine (2-fluoroadenine-beta-D-arabinofuranoside) and cladribine (2-chlorodeoxyadenosine) phosphorylation, which leads to activation of these prodrugs, commonly used for treatment of chronic lymphocytic leukemia (CLL). "
04/01/2010 - "We applied real-time PCR method to assess the mRNA expression of equilibrative and concentrative nucleoside transporter (hENT1, hCNT1), deoxycytidine and deoxyguanosine kinase (dCK, dGK), 5'-nucleotidase (5'-NT), ribonucleotide reductase catalytic and regulatory (RR1, RR2) subunits in bone marrow cells from 32 patients with Waldenström's Macroglobulinemia (WM) and small lymphocytic lymphoma (SLL) who received 2CdA-based chemotherapy. "
03/01/2003 - "We also determined the levels of deoxycytidine and deoxyguanosine kinase with radio-chemical substrate-based assays and used a high performance liquid chromatographic method to measure cellular nucleotides in leukemia cells after 2 hours' incubation. "
11/01/2002 - "We have previously reported that in a MOLT-4 leukemia cell line the acquired resistance to 9-beta-D-arabinofuranosylguanine (Ara-G) is due to deficiency of the activating enzymes deoxyguanosine kinase and deoxycytidine kinase [Biochem. "
03/01/2002 - "Real-time quantitative PCR assays for deoxycytidine kinase, deoxyguanosine kinase and 5'-nucleotidase mRNA measurement in cell lines and in patients with leukemia."
|5.||Hematologic Neoplasms (Hematological Malignancy)
01/01/2015 - "Mitochondrial deoxyguanosine kinase (dGK), is an enzyme responsible for activation of nucleoside analogs (NAs) to phosphorylated compounds which exert profound cytotoxicity, especially in hematological malignancies. "
03/01/2002 - "The relative levels of the deoxycytidine kinase (dCK), deoxyguanosine kinase (dGK), and the 5'-nucleotidase (5'-NT) are of importance for the effect of many nucleoside analogues used in the treatment of hematological malignancies. "
|2.||Messenger RNA (mRNA)
|3.||Mitochondrial DNA (mtDNA)
|6.||5'-Nucleotidase (5' Nucleotidase)
|8.||thymidine kinase 2
|9.||Nucleoside Transport Proteins (Nucleoside Transporter)
|10.||Muscle Form Glycogen Phosphorylase (Myophosphorylase)
|1.||Drug Therapy (Chemotherapy)