rehmannic acid

toxic principle, triterpene acid from Lantana camara; RN given refers to (22beta-(Z))-isomer; structure

Also Known As:

lantadene A; 22-((2-methyl-1-oxo-2-butenyl)oxy)-3-oxo-olean- 12-en-28-oic acid, (22 beta)

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Pentacyclic Triterpenes: 108
        Oleanolic Acid: 547
        rehmannic acid: 10
      - Sapogenins: 26
        Oleanolic Acid: 547
        rehmannic acid: 10

Experts

1.	Sharma, Manu: 3 articles (07/2013 - 07/2008)
2.	Lee, Hong Boon: 2 articles (07/2013 - 01/2013)
3.	Tailor, Navin Kumar: 2 articles (07/2013 - 01/2013)
4.	Al-Saffar, Ali Z: 1 article (09/2020)
5.	Jaafar, Noor Dheyaa: 1 article (09/2020)
6.	Yousif, Emad A: 1 article (09/2020)
7.	Andersen, Raymond J: 1 article (01/2018)
8.	Cho-Ngwa, Fidelis: 1 article (01/2018)
9.	Ganin's, Jessie N'kam: 1 article (01/2018)
10.	Manfo, Faustin Pascal T: 1 article (01/2018)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 09/01/2020 - "The present study was conducted to evaluate the efficiency of AuNPs in enhancing the cytotoxic and apoptotic induction activity of lantadene A (LA), separated from Lantana camara leaves, on the breast tumor cell line MCF-7 in vitro. "
2.	Poisoning 05/01/1977 - "Reduced lantadene A because of its low concentration in the leaves (5% of lantadene A) and lantadene B because of its significantly lower toxicity are thus unlikely to be of much importance in the poisoning of ruminants following consumption of the plant. " 06/01/1986 - "Lantana poisoning in ruminants results from the ingestion of toxic varieties of the plant Lantana camara, which contain the triterpene acids lantadene A and lantadene B. "
3.	Neoplasms (Cancer) 01/01/2013 - "The C-2 arylidene analog (compound 3) of pentacyclic triterpenoid Lantadene A (compound 1) was synthesized and evaluated by the National Cancer Institute, USA, for in vitro cytotoxicity against a panel of melanoma cancer cell lines: LOX IMVI, MALME-3M, M14, MDA-MB-435, SK-MEL-2, SK-MEL-28, SK-MEL-5, UACC-257 UACC-62 and B16F10. " 07/01/2013 - "The ring A and D substituted analogs of pentacyclic triterpenoid Lantadene A (1) and B (2) were synthesized and evaluated for in vitro anticancer activity against four human cancer cell lines (HL-60, MCF-7, A549 and HCT-116). "
4.	Onchocerciasis 01/01/2018 - "We report for the first time the anti-onchocercal activities of these locally consumed medicinal plants and lantadene A, a potential lead for further development as an onchocerciasis cure."
5.	Melanoma (Melanoma, Malignant) 01/01/2013 - "The C-2 arylidene analog (compound 3) of pentacyclic triterpenoid Lantadene A (compound 1) was synthesized and evaluated by the National Cancer Institute, USA, for in vitro cytotoxicity against a panel of melanoma cancer cell lines: LOX IMVI, MALME-3M, M14, MDA-MB-435, SK-MEL-2, SK-MEL-28, SK-MEL-5, UACC-257 UACC-62 and B16F10. "

Related Drugs and Biologics

1.	Triterpenes
2.	Acids
3.	lantadene B
4.	9,10-Dimethyl-1,2-benzanthracene
5.	Esters
6.	Bilirubin
7.	Acid Phosphatase
8.	Acetates (Acetic Acid Esters)
9.	lantadene C
10.	lipoarabinomannan (LAM)