3,3'-diethyloxadicarbocyanine

RN given refers to iodide; RN for parent cpd not in Chemline 6/84

Also Known As:

3,3'-diethyloxadicarbocyanine iodide; 3,3'-diethyloxadicarbocyanine, perchlorate; 3,3'-diethyloxodicarbocyanine; 3-ethyl-2-(5-(3-ethyl-2(3H)-benzoxazolylidene)- 1,3-pentadienyl)benzoxazolium iodide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkynes: 217
      - Carbocyanines: 74
        3,3'-diethyloxadicarbocyanine: 2

Experts

1.	Chang, Ai-Chi: 1 article (01/2004)
2.	Chao, Yee: 1 article (01/2004)
3.	Huang, Jen-Hsin: 1 article (01/2004)
4.	Huang, Tze-Sing: 1 article (01/2004)
5.	Hung, Yi-Mei: 1 article (01/2004)
6.	Lee, Shou-Dong: 1 article (01/2004)
7.	Li, Chung-Pin: 1 article (01/2004)
8.	Lin, Chao-Hsiung: 1 article (01/2004)
9.	Whang-Peng, Jacqueline: 1 article (01/2004)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 03/12/1999 - "Treatment of cells with the oligodeoxynucleotide TTAGGG or with 3,3'-diethyloxadicarbocyanine, agents that inhibit telomerase activity in a concentration-dependent manner, significantly enhanced mitochondrial dysfunction and apoptosis induced by staurosporine, Fe2+ (an oxidative insult), and amyloid beta-peptide (a cytotoxic peptide linked to neuronal apoptosis in Alzheimer's disease). "
2.	Pheochromocytoma 01/01/2004 - "The G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide (DODC) was reported to enhance the apoptotic potency of pheochromocytoma PC-12 and leukemia HL-60 cells through the inhibition of telomerase activity. "
3.	Leukemia 01/01/2004 - "The G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide (DODC) was reported to enhance the apoptotic potency of pheochromocytoma PC-12 and leukemia HL-60 cells through the inhibition of telomerase activity. "
4.	Alzheimer Disease (Alzheimer's Disease) 03/12/1999 - "Treatment of cells with the oligodeoxynucleotide TTAGGG or with 3,3'-diethyloxadicarbocyanine, agents that inhibit telomerase activity in a concentration-dependent manner, significantly enhanced mitochondrial dysfunction and apoptosis induced by staurosporine, Fe2+ (an oxidative insult), and amyloid beta-peptide (a cytotoxic peptide linked to neuronal apoptosis in Alzheimer's disease). "
5.	Nasopharyngeal Carcinoma 01/01/2004 - "A G-quadruplex ligand 3,3'-diethyloxadicarbocyanine iodide induces mitochondrion-mediated apoptosis but not decrease of telomerase activity in nasopharyngeal carcinoma NPC-TW01 cells."

Related Drugs and Biologics

1.	Telomerase (Telomerase Reverse Transcriptase)
2.	Staurosporine
3.	Amyloid beta-Peptides
4.	Peptides (Polypeptides)
5.	Oligodeoxyribonucleotides
6.	Ligands