|1.||Rejniuk, V L: 3 articles (11/2010 - 06/2007)|
|2.||Schaefer, T V: 2 articles (11/2010 - 11/2010)|
|3.||Ivnitsky, Ju Ju: 2 articles (11/2010 - 11/2010)|
|4.||Albrecht, Jan: 2 articles (09/2010 - 03/2004)|
|5.||Ovsep'yan, R V: 2 articles (06/2007 - 03/2007)|
|6.||Subramanian, P: 2 articles (08/2004 - 10/2002)|
|7.||Lv, Mengying: 1 article (02/2014)|
|8.||Tian, Jixin: 1 article (02/2014)|
|9.||Peng, Can: 1 article (02/2014)|
|10.||Tian, Yuan: 1 article (02/2014)|
11/01/1995 - "The study also included a single exogenous ammonium acetate (NH4Ac; 5.2 mmol/kg, i.p.) challenge to precipitate a reversible hepatic coma. "
07/01/2000 - "The brain energy metabolism of rats affected by chronic hepatic encephalopathy due to portacaval shunting was monitored by in vivo 31P-nuclear magnetic resonance spectroscopy before and after ammonium acetate administration. "
01/01/1988 - "Hepatic coma was induced in rats chronically treated with CCl4, by means of a single injection of ammonium acetate. "
06/01/1986 - "Studies were made of normal rats, rats with portacaval shunts (a model of hepatic encephalopathy), starved rats, diabetic rats, and normal rats infused with ammonium acetate. "
02/01/1995 - "In control animals not treated with either drug, but in which hepatic encephalopathy had been induced, ammonium acetate induced a comatose state defined by a loss of the righting reflex accompanied by slowing or flattening of the cortical EEG. "
11/01/1991 - "We show here that hyperammonemia affords considerable protection against depletion of hepatic energy metabolites evoked by ammonium acetate injection. "
10/15/2012 - "To determine the mechanistic relationship between hyperammonemia and autophagy, we exposed murine C(2)C(12) myotubes to ammonium acetate. "
03/01/1994 - "Hyperammonemia without any behavioural changes was induced in experimental rats by intraperitoneal administration of either a single dose (0.8 mmol/100 g wt.) or by six 'hourly' doses (0.6 mmol/100 g wt.) of ammonium acetate. "
12/13/1991 - "By contrast, and in agreement with earlier reports, hyperammonemia (variant b) did not affect D-Asp release, whereas in vitro treatment of the slices with ammonium acetate (variant c) resulted in a 60% increase of the release. "
10/01/1991 - "Effect of ammonium acetate-induced hyperammonemia on metabolism of guanidino compounds."
06/01/1998 - "These findings prompted the study of mechanisms of the protective effect of OA in portacaval-shunted rats in which reversible coma was precipitated by ammonium acetate administration (3.85 mmol/kg i.p.). "
08/01/1988 - "Administration of ammonium acetate to rats following PCA results in severe encephalopathy (loss of righting reflex and, ultimately, coma). "
01/01/1985 - "Some animals were injected with a dose of ammonium acetate sufficient to maintain coma for 1 hr (AC group). "
09/01/1984 - "Four weeks following PCA, rats were administered ammonium acetate (5.2 mmol/kg, i.p.) to precipitate neurological symptoms of encephalopathy which included diminished locomotor activity, loss of hindlimb extension and righting reflexes and ultimately coma. "
05/15/1964 - "Normal volunteers infused with ammonium acetate for 3 hours developed a characteristic behavior pattern resembling that of prehepatic coma. "
09/01/1961 - "A biometric study of the effects of ammonium acetate on electroshock convulsions."
12/20/1991 - "Administration of ammonium acetate to mice caused seizures and alterations of brain energy metabolites. "
08/01/1973 - "2. Brains were removed and frozen 5min after intraperitoneal injection of ammonium acetate (2-3min before the onset of convulsions). "
08/01/2003 - "Ammonium acetate pretreatment caused no behavioral effects per se, but potentiated MMA-induced convulsions and increased basal TBARS content and MMA-induced TBARS production in the striatum. "
03/01/1993 - "When sublethal dose of ammonium acetate (12 mmol/kg b.wt.) was injected to mice, all mice survived without developing seizures, while clear increase of brain ammonia and alterations of brain energy metabolites were seen. "
|5.||Brain Edema (Cerebral Edema)
09/01/1995 - "The lack of taurine release into extracellular fluid following ammonium acetate administration in portacaval-shunted rats could relate to the phenomenon of brain edema in these animals. "
12/01/1986 - "However, ammonium acetate infusion during mannitol-induced reversible (osmotic) opening of the blood-brain barrier (BBB) effectively induced cytotoxic brain edema. "
07/01/2001 - "In this study, noninvasive proton two-dimensional chemical shift imaging (2-D CSI) was used to follow the time course of the development of brain edema in a well characterized model, namely ammonium acetate infusion into rats 48 to 72 h after portacaval anastomosis (PCA). "
12/01/1986 - "Intravenous infusion of ammonium acetate alone into dogs did not induce brain edema, although blood ammonia reached unphysiologically high levels. "
03/01/2004 - "Treatment of cerebral cortical slices with 5mM ammonium acetate (ammonia) elevated the glutamine (Gln) content and increased cell volume in the slices, in agreement with the postulated contribution of glutamine to hyperammonemic brain edema [Neurochem. "
|2.||N-Methyl-D-Aspartate Receptors (NMDA Receptors)
|7.||Glycine (Aminoacetic Acid)
|8.||Serotonin (5 Hydroxytryptamine)
|10.||Codeine (Codeine Phosphate)
|1.||Surgical Portacaval Shunt (Portacaval Anastomosis)