ammonium acetate

11/01/1995 - "The study also included a single exogenous ammonium acetate (NH4Ac; 5.2 mmol/kg, i.p.) challenge to precipitate a reversible hepatic coma. "
02/11/2022 - "Therefore, severe acute hepatic encephalopathy induced by ammonium acetate administration caused enlargement of the ventricles, through swelling of the choroid plexus and aquaporin-1 transport and aggregation within the apical membranes."
07/16/2020 - "Hepatic encephalopathy was induced in starved rats by injection of ammonium acetate. "
07/01/2000 - "The brain energy metabolism of rats affected by chronic hepatic encephalopathy due to portacaval shunting was monitored by in vivo 31P-nuclear magnetic resonance spectroscopy before and after ammonium acetate administration. "
01/01/1988 - "Hepatic coma was induced in rats chronically treated with CCl4, by means of a single injection of ammonium acetate. "

11/01/1991 - "We show here that hyperammonemia affords considerable protection against depletion of hepatic energy metabolites evoked by ammonium acetate injection. "
02/04/2022 - "Hyperammonemia was induced in rats by ammonium acetate injection. "
10/15/2012 - "To determine the mechanistic relationship between hyperammonemia and autophagy, we exposed murine C(2)C(12) myotubes to ammonium acetate. "
03/01/1994 - "Hyperammonemia without any behavioural changes was induced in experimental rats by intraperitoneal administration of either a single dose (0.8 mmol/100 g wt.) or by six 'hourly' doses (0.6 mmol/100 g wt.) of ammonium acetate. "
01/22/1993 - "Chronic hyperammonemia was induced in rats by feeding them a diet containing 20% ammonium acetate. "

01/01/2001 - "This mechanism can be proposed to explain the protective effects of L-carnitine against adriamycin cardiotoxicity, ammonium acetate and zidovudine-induced mitochondrial ultrastructural and functional alterations. "

06/01/1998 - "These findings prompted the study of mechanisms of the protective effect of OA in portacaval-shunted rats in which reversible coma was precipitated by ammonium acetate administration (3.85 mmol/kg i.p.). "
01/01/1985 - "Some animals were injected with a dose of ammonium acetate sufficient to maintain coma for 1 hr (AC group). "
05/15/1964 - "Normal volunteers infused with ammonium acetate for 3 hours developed a characteristic behavior pattern resembling that of prehepatic coma. "
02/01/1995 - "In control animals not treated with either drug, but in which hepatic encephalopathy had been induced, ammonium acetate induced a comatose state defined by a loss of the righting reflex accompanied by slowing or flattening of the cortical EEG. "
08/01/1988 - "Administration of ammonium acetate to rats following PCA results in severe encephalopathy (loss of righting reflex and, ultimately, coma). "

09/01/1995 - "The lack of taurine release into extracellular fluid following ammonium acetate administration in portacaval-shunted rats could relate to the phenomenon of brain edema in these animals. "
12/01/1986 - "However, ammonium acetate infusion during mannitol-induced reversible (osmotic) opening of the blood-brain barrier (BBB) effectively induced cytotoxic brain edema. "
07/01/2001 - "In this study, noninvasive proton two-dimensional chemical shift imaging (2-D CSI) was used to follow the time course of the development of brain edema in a well characterized model, namely ammonium acetate infusion into rats 48 to 72 h after portacaval anastomosis (PCA). "
12/01/1986 - "Intravenous infusion of ammonium acetate alone into dogs did not induce brain edema, although blood ammonia reached unphysiologically high levels. "
03/01/2004 - "Treatment of cerebral cortical slices with 5mM ammonium acetate (ammonia) elevated the glutamine (Gln) content and increased cell volume in the slices, in agreement with the postulated contribution of glutamine to hyperammonemic brain edema [Neurochem. "