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N-acetylglucosamine-6-sulfatase

deficient in Sanfilippo syndrome type D
Also Known As:
6-sulphatase; N-acetylglucosamine-6-sulfate sulfatase; NAGSS; NAGSase; glucosamine-6-sulfatase
Networked: 17 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Suzuki, Yasuyuki: 2 articles (11/2021 - 02/2020)
2. Tomatsu, Shunji: 2 articles (11/2021 - 02/2020)
3. Cao, Henian: 2 articles (11/2007 - 01/2003)
4. Hegele, Robert A: 2 articles (11/2007 - 01/2003)
5. Cooper, Jonathan D: 1 article (12/2021)
6. Dickson, Patricia I: 1 article (12/2021)
7. Jansen, Matthew J: 1 article (12/2021)
8. Kan, Shih-Hsin: 1 article (12/2021)
9. Le, Steven Q: 1 article (12/2021)
10. Takahashi, Keigo: 1 article (12/2021)

Related Diseases

1. Mucopolysaccharidosis III (Sanfilippo Syndrome)
2. Mucopolysaccharidoses
11/01/2021 - "Mucopolysaccharidosis IVA (MPS IVA, also called Morquio A syndrome) is caused by a deficiency of N-acetylglucosamine-6-sulfate sulfatase (GALNS) and results in skeletal dysplasia symptoms such as short stature and abnormal gait. "
01/01/1992 - "N-acetylglucosamine 6-sulphatase deficiency in a Nubian goat: a model of Sanfilippo syndrome type D (mucopolysaccharidosis IIID)."
04/01/1984 - "N-Acetylglucosamine-6-sulfate sulfatase activity was assayed by incubation of the radiolabeled monosaccharide N-acetylglucosamine [1-14C]6-sulfate (GlcNAc6S) with homogenates of leukocytes and cultured skin fibroblasts and concentrates of urine derived from normal individuals, patients affected with N-acetylglucosamine-6-sulfate sulfatase deficiency (Sanfilippo D syndrome, mucopolysaccharidosis type IIID), and patients affected with other mucopolysaccharidoses. "
02/01/1989 - "N-Acetylglucosamine-6-sulfatase activity was assayed by incubation of the radiolabeled disaccharide O-(a-N-acetylglucosamine-6-sulfate)-(1----3)-L-[6-3H]-idonic acid (GlcNAc6S-IdOA), with homogenates of leucocytes, cultured fibroblasts, and urine from normal individuals, patients affected with N-acetylglucosamine-6-sulfatase-deficiency (Sanfilippo D syndrome, mucopolysaccharidosis type IIID), and patients affected with other mucopolysaccharidoses and lysosomal storage disorders. "
08/01/2017 - "Mucopolysaccharidoses type III (MPS III) are a group of autosomal recessive lysosomal storage diseases, caused by mutations in genes that code for enzymes involved in the lysosomal degradation of heparan sulphate: heparan sulfate sulfamidase (SGSH), α-Nacetylglucosaminidase (NAGLU), heparan sulfate acetyl-CoA: α-glucosaminide N-acetyltransferase (HGSNAT), and N-acetylglucosamine-6-sulfatase (GNS). "
3. Mucopolysaccharidosis IV (Morquio Syndrome)
4. Lysosomal Storage Diseases (Lysosomal Storage Disease)
5. Multiple Sulfatase Deficiency Disease (Mucosulfatidosis)

Related Drugs and Biologics

1. Enzymes
2. Heparitin Sulfate (Heparan Sulfate)
3. Sulfates (Sulfates, Inorganic)
4. Acetyltransferases
5. Acetylglucosamine
6. Acetyl Coenzyme A (Acetyl-CoA)
7. alpha-N-acetyl-D-glucosaminidase (alpha-N-acetylglucosaminidase)
8. N-sulfoglucosamine sulfohydrolase (sulfamidase)
9. Glycosaminoglycans
10. Acetylglucosaminidase (NAGase)