|1.||Kim, Seong-Jin: 1 article (05/2013)|
|2.||Hyun, Jashil: 1 article (05/2013)|
|3.||Cha, Young: 1 article (05/2013)|
|4.||Kim, Dae-Kwan: 1 article (05/2013)|
|5.||Park, Kyung-Soon: 1 article (05/2013)|
|6.||Guo, Ying: 1 article (01/2013)|
|7.||Wang, Wei: 1 article (01/2013)|
|8.||Yan, Shu-mei: 1 article (01/2013)|
|9.||Zhao, Jing-jing: 1 article (01/2013)|
|10.||Chen, Yi-bing: 1 article (01/2013)|
01/01/2008 - "In the present study, knockdown of TFIIS inhibited cancer cell proliferation, suggesting that TFIIS could be studied as a potential cancer target within the transcription machinery."
05/20/2011 - "Our findings provide a molecular mechanism for selective gene repression by RNF20 and position TFIIS as a key target of RNF20's tumor suppressor activity."
05/20/2011 - "Consistent with its positive role in transcription of pro-oncogenic genes, TFIIS expression is elevated in various human tumors. "
01/01/2008 - "Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis."
01/01/2005 - "Because the transcription elongation factor A gene has not been previously reported to be involved in cancer development, our results suggest that further investigation of its role in esophageal carcinogenesis is warranted."
|2.||Ovarian Neoplasms (Ovarian Cancer)
05/01/2013 - "The present study shows that TCEA3, an isoform of TFIIS, can trigger ovarian cancer-specific cell death by activating the JNK signaling pathway. "
08/01/2009 - "We have previously shown that TCEAL7 (transcription elongation factor A (SII)-like 7) is epigenetically down-regulated in the majority of epithelial ovarian cancers. "
|3.||Cockayne Syndrome (Syndrome, Cockayne)
01/10/2011 - "Here, silencing TFIIS using an RNA interference strategy did not affect the ability of cells to recover nascent RNA synthesis following UV exposure or the ability of cells to repair a UV-damaged reporter gene while a similar strategy to decrease the expression Cockayne syndrome group B protein (CSB) resulted in the expected repair defect. "
11/10/2010 - "Hence default TFIIS activity might mimic or contribute to the severe phenotype of Cockayne syndrome. "
02/01/2001 - "Deletion of the gene encoding the Pol II elongation factor TFIIS (SII) resulted in enhanced UV sensitivity, but only in the absence of global genome repair dependent on the RAD7 and RAD16 genes, a result seen previously with deletions of RAD26 and RAD28, yeast homologs of the human Cockayne syndrome genes CSB and CSA, respectively. "
|4.||Pancreatic Neoplasms (Pancreatic Cancer)
05/01/2013 - "Recently, knockdown of TCEA1, the most well-characterized isoform of TFIIS, by RNA silencing was reported to inhibit cancer cell proliferation and induce apoptosis in breast, lung and pancreatic cancer cell lines through activation of p53 (Hubbard et al., 2008 ). "
01/01/2008 - "Knockdown of TFIIS reduced cancer cell proliferation in breast, lung and pancreatic cancer cell lines. "
|1.||Peptide Elongation Factors (Elongation Factor)
|2.||Staphylococcal Protein A (A, Protein)
|3.||Transferrin (beta 2 Transferrin)
|4.||RNA (Ribonucleic Acid)
|5.||Proteins (Proteins, Gene)
|8.||DNA Polymerase II