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letosteine

Also Known As:

Broluidan; Viscotiol; 4-Thiazolidinecarboxylic acid, 2-(2-((2-ethoxy-2-oxoethyl)thio)ethyl)-

Networked: 4 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - Thiazolidines: 105
      - letosteine: 4

Experts

1.	Chang, Xiaoyue: 1 article (11/2014)
2.	Cui, Liying: 1 article (11/2014)
3.	Liu, Hua: 1 article (11/2014)
4.	Sun, Shenghua: 1 article (11/2014)
5.	Sun, Zhenqiu: 1 article (11/2014)
6.	Zhou, Yan: 1 article (11/2014)
7.	Fahey, T: 1 article (03/2002)
8.	Schroeder, K: 1 article (03/2002)

Related Diseases

1.	Fever (Fevers) 10/01/1989 - "The results of the study show that in the letosteine treated group there is a statistically significant decrease in fever, a favourable evolution of thoracic objectivity and an improvement in certain respiratory function parameters (MEF 75, PEF). " 10/01/1989 - "It is concluded that treatment with letosteine leads to a significant increase in the rate of regression of thoracic symptomatology and a faster, more substantial reduction in fever in children suffering from acute bronchitis. "
2.	Chronic Obstructive Pulmonary Disease (COPD) 10/08/1978 - "Thus, in this study, letosteine (50 mg t.i.d.) appeared equivalent to S-carboxy-methyl-cysteine (750 mg t.i.d.) in the treatment of chronic obstructive lung disease in adults." 10/08/1978 - "A controlled double-blind clinical trial comparing a noval medicament, letosteine, to a known bronchial fluidifier, S-carboxy-methyl-cysteine, was conducted on a total of 47 hospitalized patients suffering from various types of chronic obstructive lung disease. "
3.	Disease Progression 10/01/1989 - "A double blind vs placebo study was carried out to study the effect of letosteine on the symptoms and clinical course of paediatric patients suffering from acute febrile bronchitis. "
4.	Respiratory Tract Diseases (Respiratory Tract Disease) 11/01/2014 - "Efficacy and safety of letosteine in the treatment of sputum thickening and expectoration difficulty in patients with respiratory diseases: a multicenter, randomized, double-masked, double dummy, positive drug parallel controlled trial." 11/01/2014 - "This study aimed to compare the efficacy and safety of letosteine and ambroxol hydrochloride for the treatment of sputum thickening and expectoration difficulty due to either acute or chronic respiratory diseases. " 11/01/2014 - "Letosteine and ambroxol hydrochloride provided equivalent efficacy and safety in the treatment of sputum thickening and expectoration difficulty due to either acute or chronic respiratory diseases."
5.	Cough 03/01/2002 - "Based on a single study, the mucolytic preparation letosteine was superior to placebo, with differences in cough scores ranging from 0.1 to 0.3 points from day 4 to day 10. "

Related Drugs and Biologics

1.	Expectorants (Mucolytics)
2.	Ambroxol (Mucosolvan)
3.	mecysteine