03/01/1982 - "These data suggest that cinromide should be clinically effective, not only against tonic-clonic seizures, but also, toxicity permitting, against complex partial attacks as well."
04/01/1980 - "In both phases Cinromide's metabolite (either via BEC or especially SBC) was effective in half of the animals in reducing seizure frequency and/or duration at plasma levels above 5 mcg/m. "
08/01/1983 - "This study did not demonstrate a beneficial effect of cinromide over placebo for Type A, B, or C partial seizures. "
08/01/1983 - "Four patients withdrew from the study during or shortly after crossover to cinromide due to increased seizure frequency or severity. "
07/01/1989 - "No difference between cinromide and placebo was shown in terms of seizure reduction or global evaluations. "
08/01/1983 - "A double-blind controlled trial of cinromide in 25 adult subjects with refractory epilepsy using the maximum tolerated dose showed that it possessed no significant antiepileptic properties."
08/01/1983 - "Cinromide has previously been shown to have significant antiepileptic activity in various animal models of epilepsy. "
08/01/1983 - "Cinromide in epilepsy: a pilot study."
|3.||Absence Epilepsy (Absence Seizure)
|4.||Partial Epilepsies (Epilepsy, Partial)