emorfazone

01/01/1981 - "M73101 possessed potent inhibitory activities on acute inflammatory edema and suppressed the permeability of capillary vessels. "
03/01/1979 - "M73101 also inhibited the edema induced by mustard, scalding and anti-rat rabbit serum in rats. "
09/01/1987 - "Simultaneous treatment with stem bromelain and emorfazone decreased significantly the heat-evoked iSP release and edema. "
03/01/1979 - "In addition, the anti-edematous effect of M73101 on carrageenin-induced rat paw edema was not influenced by spinalectomy or adrenalectomy, indicating that the anti-inflammatory action of M73101 was not mediated by the central nervous system and the adrenals. "
04/20/1979 - "M73101, unlike aminopyrine and phenylbutazone, slightly increased urine volume and electrolytes excretion in rats, indicating that this compound probably does not produced edema. "

08/01/1979 - "Body weight gain, and food and water consumption were not affected due to M 73101 administration. "
05/01/1979 - "The results were summarized as follows: 1. During the dosing period, females received 300mg/kg of M73101 showed pronounced body weight depression and decrease in food and water intake. "
02/01/1978 - "There were no apparent effects of M73101 on litter size, fetal mortality or sex ratio in both species, although slight decrease in body weight occurred in fetuses of mice and rats exposed to the largest dose. "

09/01/1981 - "M73101 at an oral dose of 200 kg/mg significantly decreased the volume of exudative fluid and the number of leucocytes in carrageenin-induced pleurisy of intact rats. "
01/01/1981 - "M73101 inhibited histamine release from isolated rat mast cells (in vitro) and rat skin (in vivo) by the condensation product of N-methyl-homoanisylamine formaldehyde (compound 48/80), and leucocyte emigration in carrageenin rat pleurisy. "

05/01/1979 - "The results were summarized as follows: 1. No significant effects of M73101 on number of the corpora lutea, litter size, fetal mortality, fetal weight or sex ratio were observed, but aspirin exhibited the intrauterine deaths and growth retardation in fetuses. "

01/01/1992 - "Double blind study on emorfazone and ibuprofen in dental pain and inflammation."