|1.||Zhang, Yanmin: 8 articles (11/2015 - 04/2008)|
|2.||He, Langchong: 8 articles (05/2014 - 07/2005)|
|3.||Wang, Nan: 6 articles (05/2014 - 07/2011)|
|4.||Zhan, Yingzhuan: 5 articles (01/2015 - 09/2011)|
|5.||Zheng, Lei: 5 articles (05/2014 - 09/2011)|
|6.||Dai, Bingling: 4 articles (11/2015 - 11/2011)|
|7.||Chen, Yinnan: 4 articles (05/2014 - 09/2011)|
|8.||Zhang, Jie: 4 articles (07/2012 - 11/2011)|
|9.||Liu, Rui: 3 articles (11/2015 - 01/2015)|
|10.||Wang, Wenjie: 2 articles (11/2015 - 03/2015)|
04/08/2008 - "The present study was to demonstrate the effect of taspine isolated from Radix et Rhizoma Leonticis on tumor angiogenesis and its mechanism of action. "
12/18/2012 - "Both sap and taspine inhibited cancer cell proliferation; taspine showed higher activity on SK23 cells, which was significantly increased after 48 h of SK23 treatment. "
01/01/2012 - "Taspine, isolated from Radix et Rhizoma Leonticis has demosntrated potential proctiective effects against cancer. "
07/01/2008 - "The molecular mechanism(s) of taspine on tumor angiogenic inhibition have not been well documented. "
07/01/2008 - "Taspine is an active component isolated from Radix et Rhizoma Leonticis with inhibiting tumor angiogenic properties. "
|2.||Breast Neoplasms (Breast Cancer)
05/01/2014 - "A novel taspine derivative, HMQ1611, suppresses adhesion, migration and invasion of ZR-75-30 human breast cancer cells."
06/01/2012 - "Here, we report a novel taspine derivative, HMQ1611, which has anticancer effects using in vitro and in vivo breast cancer models. "
09/01/2011 - "Taken together, these results suggested that taspine might serve as a promising candidate of ER antagonist in the treatment of oestrogen-independent breast cancer."
09/01/2011 - "The aim of our study was to investigate the effect of taspine isolated from Radix et Rhizoma Leonticis on the growth of oestrogen-receptor-positive breast cancer xenografts in vivo and the possible mechanism for this action. "
07/01/2012 - "Synthesis of novel taspine diphenyl derivatives as fluorescence probes and inhibitors of breast cancer cell proliferation."
|3.||Liver Neoplasms (Liver Cancer)
11/01/2015 - "The present study investigated the effects of TAS9, a modified taspine derivative, on the proliferation and migration of the SMMC‑7721 human liver cancer cell line. "
07/01/2011 - "To analyse the inhibition effect of taspine derivatives on human Liver cancer SMMC7721 cell and its mechanism. "
07/01/2011 - "[Effect of taspine derivatives on human liver cancer SMMC7721]."
07/01/2011 - "The taspine derivative Tas-D1 can inhibit the growth of human Liver cancer SMMC7721 cell and change cell cycle, which may be related to the inhibition of EGF and VEGF expression."
|4.||Hepatocellular Carcinoma (Hepatoma)
01/01/2015 - "In present study, we report that TADs, a novel derivative of taspine, has an essential role in resisting hepatocellular carcinoma growth (including arrest cell cycle) and migration, and inducing cell apoptosis. "
11/01/2015 - "Taspine derivative TAS9 regulates cell growth and metastasis of human hepatocellular carcinoma."
|5.||Sarcoma (Soft Tissue Sarcoma)
05/01/2007 - "To study the inhibition effect of taspine on mouse S180 sarcoma and its mechanism. "
05/01/2007 - "Taspine showed antitumor activity on the mouse S180 sarcoma in a good dose-dependent manner. "
05/01/2007 - "The mouse S180 sarcoma model was established and used to observe the antitumor activity of taspine. "
05/01/2007 - "[Inhibitory effect of taspine on mouse S180 sarcoma and its mechanism]."
05/01/2007 - "Taspine has antitumor effect on the S180 sarcoma, and the mechanism may be through the way of decreasing the expressing of the VEGF, bFGF, Bcl-2 and Bax and inducing the vascular endothelial cell apoptosis."
|2.||Progesterone Receptors (Progesterone Receptor)
|3.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|4.||Messenger RNA (mRNA)
|6.||Vinblastine (Vinblastine Sulfate)
|8.||Epidermal Growth Factor Receptor (EGF Receptor)
|9.||Epidermal Growth Factor (EGF)
|10.||Type I DNA Topoisomerases (Topoisomerase I)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Transplantation (Transplant Recipients)
|3.||Traditional Medicine (Folk Remedies)