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quelamycin
Also Known As:
NSC-267703; triferric doxorubicin
Networked:
5
relevant articles (
0
outcomes,
2
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
Daunorubicin: 2641
Doxorubicin: 35390
quelamycin: 5
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthacenes
Anthracyclines: 9423
Daunorubicin: 2641
Doxorubicin: 35390
quelamycin: 5
Carbohydrates: 22023
Glycosides: 2119
Aminoglycosides: 5131
Anthracyclines: 9423
Daunorubicin: 2641
Doxorubicin: 35390
quelamycin: 5
Experts
1.
Gosálvez Gosálvez, M
: 1 article (01/2000)
Related Diseases
1.
Cardiotoxicity
05/01/1979 - "
A previous phase I study demonstrated excessive generalized toxicity (20 of 21 patients) and cardiotoxicity (eight of 21 patients) of single-day intermittent quelamycin (NSC-267703) treatment, and a modified schedule was recommended to overcome this acute toxicity.
"
01/01/1980 - "
Quelamycin is triferric doxorubicin, a metallic derivative of adriamycin which, in experimental studies, has been found to have a better therapeutic index than adriamycin and no cardiotoxicity.
"
2.
Neoplasms (Cancer)
05/01/1979 - "
Our phase I clinical study of quelamycin includes 37 patients with a wide spectrum of solid tumors.
"
01/01/2000 - "
It is defined the precise responsibility of the author in the discoveries of the second site of control of glycolysis, rotenone tumors, quelamycin and thioproline, filamentous mitochondria, and the technique of cancer reversal by dual strategy.
"
3.
Hyperthermia
02/01/1985 - "
With the MM cells, hyperthermia potentiated the cytotoxic effects of doxorubicin (ADM), daunorubicin, mitoxantrone (DHAD), and quelamycin but did not enhance that of aclacinomycin (ACM).
"
Related Drugs and Biologics
1.
quelamycin
2.
Doxorubicin (Adriamycin)
3.
Rotenone
4.
Mitoxantrone (Novantrone)
5.
Daunorubicin (Cerubidine)
6.
aclacinomycins
7.
thiazolidine-4-carboxylic acid