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3-deazaadenosine

RN given refers to parent cpd.

Also Known As:

3-deazaadenosine hydrochloride

Networked: 24 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Tubercidin: 42
        3-deazaadenosine: 24
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Tubercidin: 42
      - 3-deazaadenosine: 24
  - Ribonucleosides: 49
    - Tubercidin: 42
      - 3-deazaadenosine: 24

Experts

1.	Fink, Ludger: 2 articles (05/2009 - 12/2003)
2.	Haberbosch, Werner: 2 articles (05/2009 - 12/2003)
3.	Walker, Gerhard: 2 articles (05/2009 - 12/2003)
4.	Fang, Min: 1 article (01/2022)
5.	Huang, Huanghuang: 1 article (01/2022)
6.	Li, Zezhi: 1 article (01/2022)
7.	Liu, Xueyuan: 1 article (01/2022)
8.	Xu, Chenhaoyi: 1 article (01/2022)
9.	Zhang, Min: 1 article (01/2022)
10.	Zhang, Pei: 1 article (01/2022)

Related Diseases

1.	Inflammation (Inflammations) 08/15/2019 - "The aim of this study was to determine the role of EZH2 in microglia-associated inflammation in ischaemic stroke and to further detect the effects of the EZH2 inhibitor, 3-deazaadenosine A (DZNep), in ischaemic brain injury. "
2.	Brain Injuries (Brain Injury) 08/15/2019 - "The aim of this study was to determine the role of EZH2 in microglia-associated inflammation in ischaemic stroke and to further detect the effects of the EZH2 inhibitor, 3-deazaadenosine A (DZNep), in ischaemic brain injury. "
3.	Ischemic Stroke 08/15/2019 - "The aim of this study was to determine the role of EZH2 in microglia-associated inflammation in ischaemic stroke and to further detect the effects of the EZH2 inhibitor, 3-deazaadenosine A (DZNep), in ischaemic brain injury. "
4.	Leukemia 12/31/2000 - "Induction of apoptosis in human leukemia cells by 3-deazaadenosine is mediated by caspase-3-like activity." 06/01/1994 - "The effect of exogenous homocysteine thiolactone (Hcy) on apoptosis initiated by 3-deazaadenosine (c3Ado) was studied in human leukemia HL-60 cells. " 12/03/1993 - "Cell death initiated by the adenosine analog 3-deazaadenosine (c3 Ado) was studied in human promyelocytic leukemia HL-60 cells. " 10/09/1991 - "Effects of the transmethylation inhibitors 3-deazaadenosine (c3Ado) and 3-deaza-(+/-)-aristeromycin (c3Ari) on cell cycle and cyclic AMP (cAMP) concentrations in human promyelocytic leukemia cells (HL-60) were studied by flow cytometry and radioimmunoassay techniques. " 01/01/1989 - "The adenosine analogue 3-deazaadenosine (c3 Ado) induces differentiation of human promyelocytic leukemia HL-60 cells in vitro. "
5.	Neointima 05/22/2009 - "3-Deazaadenosine prevents smooth muscle cell proliferation and neointima formation by interfering with Ras signaling." 01/23/2009 - "The nucleotide analogue 3-deazaadenosine prevents neointima-formation after balloon injury."

Related Drugs and Biologics

1.	3-deazaneplanocin
2.	beta-apocarotenoid-14',13'-dioxygenase (ADO)
3.	Adenosine (Adenocard)
4.	aristeromycin
5.	homocysteine thiolactone
6.	S-Adenosylhomocysteine
7.	Hydrolases
8.	NF-kappa B (NF-kB)
9.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10.	S-Adenosylmethionine (Ademetionine)